The Importance of Long-term Acute Care Hospitals in the Regional Epidemiology of Klebsiella pneumoniae Carbapenemase–Producing Enterobacteriaceae
| العنوان: | The Importance of Long-term Acute Care Hospitals in the Regional Epidemiology of Klebsiella pneumoniae Carbapenemase–Producing Enterobacteriaceae |
|---|---|
| المؤلفون: | Michael Y. Lin, Rosie D. Lyles-Banks, Karen Lolans, David W. Hines, Joel B. Spear, Russell Petrak, William E. Trick, Robert A. Weinstein, Mary K. Hayden, Ninfa Acuna, Rosemary Albright, Pat Alexander, Therese Anthony, Laura Bardowski, Cate Berends, Amanda Bonebrake, Judy Bova, Annie Braggs, Stephanie Burtun, Mary Alice Byrnes, Carol Cagle, Rose Chavis, Sue Cienkus, Sheila Collins-Johnson, Cari Coomer, Theresa Chou, Diane Cullen, Delia DeGuzman, Onofre Donceras, Margaret Feller, Sharon Fung, Jo Anne Marie Gasienica, Silvia Garcia-Houchins, Gerry Genovese, Marge Gentile, Gregg Gonzaga, Edward Goodwin, Elsie Hernandez, James Kerridge, Jean Kirk, Mary Alice Lavin, Susan Lee, Jan Lepinski, Sandra Myrick, Toni Oats, Anna O'Donnell, Violetta Pasinos, Jo Ann Patton, Maria Perez, Joanne Purpura, Linda Rakoski, Sandra Reiner, Asif Saiyed, Mary Santine, Barbara Schmitt, Carol Schultz, Rose Marie Semar, Helen Sethuraman, Chris Silkaitis, Elizabeth Stutler, Annie Thompson, Katie Wickman, Maureen Bolon, Andrew Cha, Emily Landon, James Malow, Sunita Mohapatra, John Segreti, Stephen Weber, Sharon Welbel, Teresa Zembower |
| المصدر: | Clinical Infectious Diseases. 57:1246-1252 |
| بيانات النشر: | Oxford University Press (OUP), 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Adult, Male, Microbiology (medical), medicine.medical_specialty, Pediatrics, Time Factors, Klebsiella pneumoniae, Prevalence, Carbapenem-resistant enterobacteriaceae, beta-Lactamases, law.invention, Bacterial Proteins, Enterobacteriaceae, law, Acute care, Intensive care, Epidemiology, medicine, Humans, Colonization, Aged, Chicago, Cross Infection, biology, business.industry, Enterobacteriaceae Infections, Middle Aged, biology.organism_classification, Intensive care unit, Hospitals, Infectious Diseases, Carrier State, Emergency medicine, Female, Patient Care, business |
| الوصف: | Background In the United States, Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae are increasingly detected in clinical infections; however, the colonization burden of these organisms among short-stay and long-term acute care hospitals is unknown. Methods Short-stay acute care hospitals with adult intensive care units (ICUs) in the city of Chicago were recruited for 2 cross-sectional single-day point prevalence surveys (survey 1, July 2010-January 2011; survey 2, January-July 2011). In addition, all long-term acute care hospitals (LTACHs) in the Chicago region (Cook County) were recruited for a single-day point prevalence survey during January-May 2011. Swab specimens were collected from rectal, inguinal, or urine sites and tested for Enterobacteriaceae carrying blaKPC. Results We surveyed 24 of 25 eligible short-stay acute care hospitals and 7 of 7 eligible LTACHs. Among LTACHs, 30.4% (119 of 391) of patients were colonized with KPC-producing Enterobacteriaceae, compared to 3.3% (30 of 910) of short-stay hospital ICU patients (prevalence ratio, 9.2; 95% confidence interval, 6.3-13.5). All surveyed LTACHs had patients harboring KPC (prevalence range, 10%-54%), versus 15 of 24 short-stay hospitals (prevalence range, 0%-29%). Several patient-level covariates present at the time of survey-LTACH facility type, mechanical ventilation, and length of stay-were independent risk factors for KPC-producing Enterobacteriaceae colonization. Conclusions We identified high colonization prevalence of KPC-producing Enterobacteriaceae among patients in LTACHs. Patients with chronic medical care needs in long-term care facilities may play an important role in the spread of these extremely drug-resistant pathogens. |
| تدمد: | 1537-6591 1058-4838 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb318a38d1aeff6fcdc8070dc9b62285 https://doi.org/10.1093/cid/cit500 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....cb318a38d1aeff6fcdc8070dc9b62285 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15376591 10584838 |
|---|