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Induction of Transcriptional Inhibitor HES1 and the Related Repression of Tumor-Suppressor TXNIP Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase NPM-ALK

التفاصيل البيبلوغرافية
العنوان: Induction of Transcriptional Inhibitor HES1 and the Related Repression of Tumor-Suppressor TXNIP Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase NPM-ALK
المؤلفون: Qian Zhang, Hong Y. Wang, Anindita Nayak, Selene Nunez-Cruz, Artur Slupianek, Xiaobin Liu, Johnvesly Basappa, Jing-Song Fan, Seble Chekol, Reza Nejati, Agata M. Bogusz, Suzanne D. Turner, Kunchithapadam Swaminathan, Mariusz A. Wasik
المصدر: The American Journal of Pathology. 192:1186-1198
بيانات النشر: Elsevier BV, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Carcinogenesis, Cell Line, Tumor, Humans, Transcription Factor HES-1, Anaplastic Lymphoma Kinase, Oncogenes, Phosphorylation, Carrier Proteins, Lymphoma, T-Cell, Pathology and Forensic Medicine
الوصف: This study reports that hairy and enhancer of split homolog-1 (HES1), known to repress gene transcription in progenitor cells of several cell lineages, was strongly expressed in cells and tissues of T-cell lymphoma expressing the oncogenic chimeric tyrosine kinase nucleophosmin (NPM)-anaplastic lymphoma kinase [ALK; ALK
تدمد: 0002-9440
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7b59cd3824df707d344b6dc115a79e
https://doi.org/10.1016/j.ajpath.2022.05.005
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....cc7b59cd3824df707d344b6dc115a79e
قاعدة البيانات: OpenAIRE
الوصف
تدمد:00029440