Platelet Function Tests Predicting the Efficacy and Safety of Aspirin Secondary Prevention
| العنوان: | Platelet Function Tests Predicting the Efficacy and Safety of Aspirin Secondary Prevention |
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| المؤلفون: | Weihong Ge, Tengfei Shao, Yun Xu, Yue Cheng, Meijuan Zhang, Hengheng Xu, Dan Yang, Pengfei Shao, Lili Huang |
| المصدر: | Neurological Research. 44:291-298 |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Blood Platelets, Male, medicine.medical_specialty, Platelet Function Tests, Gastroenterology, Internal medicine, Outcome Assessment, Health Care, Secondary Prevention, medicine, Humans, Platelet, Stroke, Aged, Cerebral Hemorrhage, Ischemic Stroke, Aged, 80 and over, Aspirin, medicine.diagnostic_test, Receiver operating characteristic, business.industry, Area under the curve, General Medicine, Middle Aged, medicine.disease, Clopidogrel, Thromboelastography, Platelet function test, Neurology, Drug Therapy, Combination, Female, Neurology (clinical), business, Platelet Aggregation Inhibitors, Follow-Up Studies, medicine.drug |
| الوصف: | OBJECTIVE To precisely prevent stroke, we evaluated three platelet function tests and their associations with clinical outcomes in ischemic stroke patients. METHODS On-treatment platelet reactivity of acute minor stroke patients taking aspirin plus clopidogrel was tested by light transmittance aggregometry (LTA), thromboelastography (TEG) and platelet function analyzer (PFA). Mann-Whitney U tests and receiver operating characteristic (ROC) curve analysis were used to assess their associations with recurrent events and clinical outcome prediction. RESULTS 127 acute minor stroke patients were stringently selected and followed for 13 months. Eight patients (6.3%) self-reported the recurrence and 13 (10.2%) patients self-reported bleeding. Recurrent patients displayed significantly higher on-treatment platelet reactivity when measured with LTA (p = 0.030) and PFA (p |
| تدمد: | 1743-1328 0161-6412 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc981c34f5a49976cd460887e269971e https://doi.org/10.1080/01616412.2021.1981103 |
| رقم الأكسشن: | edsair.doi.dedup.....cc981c34f5a49976cd460887e269971e |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 17431328 01616412 |
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