Supracellular migration – beyond collective cell migration
| العنوان: | Supracellular migration – beyond collective cell migration |
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| المؤلفون: | Roberto Mayor, Adam Shellard |
| المصدر: | Journal of Cell Science. 132 |
| بيانات النشر: | The Company of Biologists, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Cognitive science, 0303 health sciences, Collective cell migration, Cell Polarity, Tissue level, Cell Biology, Biology, Cellular level, Collective migration, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Cell Adhesion, Animals, Humans, 030217 neurology & neurosurgery, 030304 developmental biology |
| الوصف: | Collective cell migration is a highly complex process in which groups of cells move together. A fundamental question is how cell ensembles can migrate efficiently. In some cases, the group is no more than a collection of individual cells. In others, the group behaves as a supracellular unit, whereby the cell group could be considered as a giant ‘supracell’, the concept of which was conceived over a century ago. The development of recent tools has provided considerable evidence that cell collectives are highly cooperative, and their migration can better be understood at the tissue level, rather than at the cell level. In this Review, we will define supracellular migration as a type of collective cell migration that operates at a scale higher than the individual cells. We will discuss key concepts of supracellular migration, review recent evidence of collectives exhibiting supracellular features and argue that many seemingly complex collective movements could be better explained by considering the participating cells as supracellular entities. |
| تدمد: | 1477-9137 0021-9533 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb2c1f530ebe3820146090df8954cc2 https://doi.org/10.1242/jcs.226142 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....cdb2c1f530ebe3820146090df8954cc2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14779137 00219533 |
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