Acute Effects of Maternal Stress on Fetal Blood Catecholamines and Hypothalamic LH-RH Content
العنوان: | Acute Effects of Maternal Stress on Fetal Blood Catecholamines and Hypothalamic LH-RH Content |
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المؤلفون: | Tomi Ohkawa, K. Dobashi, S. Okinaga, Wolfgang Rohde, K. Arai, Günter Dörner |
المصدر: | Experimental and Clinical Endocrinology & Diabetes. 82:268-274 |
بيانات النشر: | Georg Thieme Verlag KG, 2009. |
سنة النشر: | 2009 |
مصطلحات موضوعية: | medicine.medical_specialty, Epinephrine, Dopamine, Endocrinology, Diabetes and Metabolism, Hypothalamus, Peptide hormone, Biology, Gonadotropin-Releasing Hormone, Norepinephrine (medication), Norepinephrine, chemistry.chemical_compound, Catecholamines, Endocrinology, Pregnancy, Stress, Physiological, Internal medicine, Adrenal Glands, Internal Medicine, medicine, Animals, Neurotransmitter, Fetus, Rats, Inbred Strains, General Medicine, Fetal Blood, Rats, chemistry, Catecholamine, Female, medicine.drug |
الوصف: | The acute effects of maternal stress (restraint for 20 to 140 min) on the plasma levels of epinephrine, norepinephrine and dopamine in pregnant rats and their fetuses as well as on the catecholamine content of fetal adrenals and the LH-RH content of fetal hypothalami, were investigated at day 22 of gestation. Despite of a relatively moderate increase of maternal plasma catecholamines a significant increase of norepinephrine (p less than 0.05) and dopamine (p less than 0.05) levels in plasma of the fetuses 30 min after starting maternal stress was observed. The fetal blood concentrations of catecholamines before and during maternal stress were significantly higher than those of the mothers (p less than 0.05 to p less than 0.001). A gradual decrease of the fetal adrenal content of epinephrine and norepinephrine was found, whereas an unchanged content of dopamine of fetal adrenals was registered during maternal restraining. The LH-RH content of fetal hypothalami rose significantly (p less than 0.005) 60 min after starting maternal stress and returned to initial values 140 min after starting restraining. |
تدمد: | 1439-3646 0947-7349 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0378a9ff4d8de9b7496b20769b0ee41 https://doi.org/10.1055/s-0029-1210286 |
رقم الأكسشن: | edsair.doi.dedup.....d0378a9ff4d8de9b7496b20769b0ee41 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14393646 09477349 |
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