Review of Inhaled Nitric Oxide in the Pediatric Cardiac Surgery Setting
| العنوان: | Review of Inhaled Nitric Oxide in the Pediatric Cardiac Surgery Setting |
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| المؤلفون: | Brahm Goldstein, Ronald A. Bronicki, Paul A. Checchia |
| المصدر: | Pediatric Cardiology. 33:493-505 |
| بيانات النشر: | Springer Science and Business Media LLC, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Heart Defects, Congenital, medicine.medical_specialty, Heart disease, Hypertension, Pulmonary, Context (language use), Nitric Oxide, law.invention, Nitric oxide, chemistry.chemical_compound, law, Administration, Inhalation, medicine, Cardiopulmonary bypass, Humans, Cardiac Surgical Procedures, Child, Intensive care medicine, Endothelium-Dependent Relaxing Factors, business.industry, Vascular surgery, medicine.disease, Pulmonary hypertension, Cardiac surgery, Clinical trial, chemistry, Pediatrics, Perinatology and Child Health, Vascular Resistance, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Surgical intervention for congenital heart disease (CHD) can be complicated by pulmonary hypertension (PH), which increases morbidity, mortality, and medical burden. Consequently, postoperative management of PH is an important clinical consideration to improve outcomes. Inhaled nitric oxide (iNO) is a widely accepted standard of care for PH and has been studied in the context of cardiac surgery for CHD. However, large randomized, double-blind, placebo-controlled, multicenter clinical trials in pediatric patients are limited. This review will provide an overview of the clinical studies in this setting and will discuss general treatment considerations to facilitate a better understanding of the clinical use of iNO for PH after pediatric cardiac surgery. |
| تدمد: | 1432-1971 0172-0643 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d283d2967d645a1a99dd7384e76ee72e https://doi.org/10.1007/s00246-012-0172-4 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....d283d2967d645a1a99dd7384e76ee72e |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14321971 01720643 |
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