In article number https://doi.org/10.1002/advs.201700402, Eben Alsberg and co‐workers report the engineering of tri‐tissue tracheas using a scaffold‐free approach that allows for the integration of structural cartilage rings, prevascular blood vessel networks, and epithelial cells into a single construct. Neotracheas of various dimensions, including human size, are formed via cellular self‐assembly. Prevascular tracheas are subcutaneously implanted into mice and demonstrate anastamosis with and perfusion by host vasculature.
