التفاصيل البيبلوغرافية
العنوان:
Syntheses of novel myxopyronin B analogs as potential inhibitors of bacterial RNA polymerase
المؤلفون:
Stephen E. Webber , Amit M. Shah , Kevin R. Steffy , James R. Appleman , Alan X. Xiang , Robert M. Aust , Thomas Doundoulakis , Richard E. Showalter , Klaus B. Simonsen , William T. Biller , Virginia N. Banh , Wes Sisson , Ricardo Lira , Konstantinos A. Agrios
المصدر:
Bioorganic & Medicinal Chemistry Letters . 17:6797-6800
بيانات النشر:
Elsevier BV, 2007.
سنة النشر:
2007
مصطلحات موضوعية:
Staphylococcus aureus , Clinical Biochemistry , Pharmaceutical Science , medicine.disease_cause , Methylation , Biochemistry , Microbiology , Inhibitory Concentration 50 , Lactones , chemistry.chemical_compound , RNA polymerase , Drug Discovery , Escherichia coli , medicine , Enzyme Inhibitors , Molecular Biology , Polymerase , Antibacterial agent , chemistry.chemical_classification , Molecular Structure , biology , Organic Chemistry , DNA-Directed RNA Polymerases , Anti-Bacterial Agents , Enzyme , chemistry , Myxopyronin , biology.protein , Molecular Medicine , Antibacterial activity
الوصف:
Based upon observations from our initial findings, additional myxopyronin B analogs have been prepared and tested for in vitro inhibitory activity against DNA-dependent RNA polymerase and antibacterial activity against Escherichia coli and Staphylococcus aureus.
تدمد:
0960-894X
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cb065632e8fb157a6e76b6add4692a https://doi.org/10.1016/j.bmcl.2007.10.017
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi.dedup.....d3cb065632e8fb157a6e76b6add4692a
قاعدة البيانات:
OpenAIRE
