Acute release of catecholamines on circulating blood cell adrenoceptors and metabolic indices in dog
| العنوان: | Acute release of catecholamines on circulating blood cell adrenoceptors and metabolic indices in dog |
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| المؤلفون: | J. Cotonat, Jean-Louis Montastruc, Philippe Valet, Christine Damase-Michel, M. Taouis, Paul Montastruc |
| المساهمون: | Biologie de l'adipocyte, physiologie du tissu adipeux et obésités, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut Louis Bugnard-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), PERIGNON, Alain |
| المصدر: | Fundamental & Clinical Pharmacology Fundamental & Clinical Pharmacology, 1988, 2 (4), pp.267-276. ⟨10.1111/j.1472-8206.1988.tb00638.x⟩ |
| سنة النشر: | 1988 |
| مصطلحات موضوعية: | Blood Glucose, Male, MESH: Receptors, Adrenergic, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.NEU.PC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Fatty Acids, Nonesterified, MESH: Yohimbine, MESH: Dogs, MESH: Hormones, Catecholamines, Blood plasma, Leukocytes, MESH: Animals, Pharmacology (medical), Platelet, Iodocyanopindolol, MESH: Blood Platelets, Sinoatrial Node, chemistry.chemical_classification, MESH: Fatty Acids, Nonesterified, [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, Yohimbine, Neurogenic hypertension, Receptors, Adrenergic, MESH: Iodocyanopindolol, Alpha-2 adrenergic receptor, Female, MESH: Sinoatrial Node, medicine.drug, Blood Platelets, MESH: Hemodynamics, medicine.medical_specialty, Adrenergic receptor, In Vitro Techniques, MESH: Pindolol, MESH: Leukocytes, Dogs, Internal medicine, MESH: Catecholamines, medicine, Animals, MESH: In Vitro Techniques, Pharmacology, Blood Cells, business.industry, MESH: Blood Cells, Cell Membrane, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Hemodynamics, Fatty acid, MESH: Male, Hormones, Endocrinology, chemistry, Pindolol, MESH: Blood Glucose, Catecholamine, business, MESH: Female, [SDV.NEU.SC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, MESH: Cell Membrane |
| الوصف: | International audience; The effects of acute release of endogenous catecholamines on both platelet alpha 2 and leukocyte beta adrenoreceptors and metabolic indices (glucose and free fatty acids) were investigated in dogs by means of a model of neurogenic hypertension following acute sinoaortic denervation (ASAD). Despite the marked increase in catecholamine levels (+4.2-fold for noradrenaline and 16.7-fold for adrenaline, for example, at minute 45 following ASAD) and in glucose plasma levels, and the significant decrease in free fatty acid plasma levels, no change in platelet alpha 2 or leukocyte beta adrenoreceptor binding sites (number as well as affinity) was observed during the whole experiment. It is suggested that the number of platelet alpha 2- and leukocyte beta-adrenoreceptors is not submitted to short-term regulation, at least by endogenous catecholamines in dogs. |
| تدمد: | 0767-3981 1472-8206 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4eadd2351adb56debc303c936b13024 https://pubmed.ncbi.nlm.nih.gov/3220423 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....d4eadd2351adb56debc303c936b13024 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 07673981 14728206 |
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