Evaluation of fetal lung maturity by measurement of the procoagulant activity in amniotic fluid
| العنوان: | Evaluation of fetal lung maturity by measurement of the procoagulant activity in amniotic fluid |
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| المؤلفون: | H. Heyes, K. Musch, W. Leucht |
| المصدر: | Archives of Gynecology. 233:7-14 |
| بيانات النشر: | Springer Science and Business Media LLC, 1982. |
| سنة النشر: | 1982 |
| مصطلحات موضوعية: | medicine.medical_specialty, Amniotic fluid, Gestational Age, Betamethasone, Equivalent, Fetal Organ Maturity, Pregnancy, Internal medicine, medicine, Humans, Lung, business.industry, Obstetrics and Gynecology, Gestational age, General Medicine, Amniotic Fluid, medicine.disease, Endocrinology, medicine.anatomical_structure, Coagulation, Fetal lung maturity, Prothrombin Time, Female, business, medicine.drug |
| الوصف: | The procoagulant activity of amniotic fluid (AF) increases with advancing gestational age. AF samples (N = 276) were measured by a modified recalcification time method. The results were expressed as equivalents of Russell's viper venom (RVV) which acts in a similar way as AF by way of direct activation of coagulation factor X. After week 35 of pregnancy RVV values reached or passed 0.09 micrograms/ml. This value represents a threshold indicating fetal lung maturity. In 124 cases postnatal lung maturity was related to RVV equivalents. The predictive value of a mature result was 99.1%, that of an immature one 52.2%. When comparing RVV values with the lung status, surface tension measurements, and L/S ratio a high correlation was found. L/S ratio and procoagulant activity had a correlation coefficient of r = 0.60. Betamethasone seemed to produce the expected changes in the results of RVV assays and surface tension measurements. |
| تدمد: | 1432-0711 0170-9925 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ca0f64fb2bd524740680fa18587b5b https://doi.org/10.1007/bf02110673 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....d5ca0f64fb2bd524740680fa18587b5b |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14320711 01709925 |
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