Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism
| العنوان: | Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
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| المؤلفون: | Özcan Özkan, F. Bakir, S. Adiguzel |
| المصدر: | Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 1, Pp 45-57 (2008) Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 14, Issue: 1, Pages: 45-57, Published: 2008 Journal of Venomous Animals and Toxins including Tropical Diseases v.14 n.1 2008 The Journal of venomous animals and toxins including tropical diseases Universidade Estadual Paulista (UNESP) instacron:UNESP |
| بيانات النشر: | FapUNIFESP (SciELO), 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, Globulin, lcsh:RC955-962, venom, Venom, Toxicology, complex mixtures, chemistry.chemical_compound, lcsh:RA1190-1270, Buthidae, Lactate dehydrogenase, Internal medicine, lcsh:Zoology, medicine, lcsh:QL1-991, lcsh:Toxicology. Poisons, scorpions, biology, Androctonus crassicauda, Albumin, biology.organism_classification, rats, Infectious Diseases, Endocrinology, chemistry, Biochemistry, Toxicity, biology.protein, Uric acid, Alkaline phosphatase, biochemical parameters, Animal Science and Zoology, Parasitology |
| الوصف: | Scorpions are venomous arthropods of the Arachnida class and are considered relatives of spiders, ticks and mites. There is not any study about the biochemical effects of Androctonus crassicauda (Olivier, 1807) venom. Therefore, in the present study, we aimed at evaluating the toxicity of the venom from A. crassicauda, which is responsible for a number of deaths of infants, children and adults in tropical and subtropical countries. For this purpose, rats (n=35) were divided into seven groups of five animals each; venom solutions (250µg/kg) were subcutaneously injected into rats; blood samples were taken from each animal at various times; and serum biochemical parameters were measured (levels of total proteins, total bilirubin, albumin, globulin, urea, creatinine, uric acid, glucose, cholesterol, triglycerides, sodium, chlorine, potassium and calcium, and the activity of the enzymes alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase). Serum levels of glucose, cholesterol, aspartate aminotransferase, alanine aminotransferase and uric acid increased in envenomed animals, compared to controls. There was a statistically positive correlation between Na+ and Cl- ions. |
| وصف الملف: | text/html |
| تدمد: | 1678-9199 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d3aa5ac99aecc1f4b420e22601aaef https://doi.org/10.1590/s1678-91992008000100004 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....d6d3aa5ac99aecc1f4b420e22601aaef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16789199 |
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