Atropisomeric Chiral Diiododienes (Z,Z)-2,3-Di(1-iodoalkylidene)tetralins: Synthesis, Enantiomeric Resolution, and Application in Asymmetric Catalysis
| العنوان: | Atropisomeric Chiral Diiododienes (Z,Z)-2,3-Di(1-iodoalkylidene)tetralins: Synthesis, Enantiomeric Resolution, and Application in Asymmetric Catalysis |
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| المؤلفون: | Yuta Amano, Kiyohiko Nakajima, Naoko Takenaga, Hao Hu, Toshifumi Dohi, Tamotsu Takahashi, Masamichi Ogasawara, Yasuyuki Kita, Hirotaka Sasa, Hikaru Nakajima |
| المصدر: | Organic Letters. 19:4102-4105 |
| بيانات النشر: | American Chemical Society (ACS), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Resolution (mass spectrometry), 010405 organic chemistry, Stereochemistry, Organic Chemistry, Enantioselective synthesis, 010402 general chemistry, Chiral stationary phase, 01 natural sciences, Biochemistry, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Tetralin, Physical and Theoretical Chemistry, Enantiomer, Chiral derivatizing agent |
| الوصف: | The C2-symmetric tetralin-fused 1,4-diiodo-1,3-butadiene derivatives, (Z,Z)-2,3-di(1-iodoalkylidene)tetralin 1a-c, are atropisomeric and can be resolved into the two persistent axially chiral enantiomers by HPLC on a chiral stationary phase. The enantiomerically pure compounds can serve as chiral organocatalysts for dearomatizing spirolactonization to show good performances in up to 73 % ee. |
| وصف الملف: | application/pdf |
| تدمد: | 1523-7052 1523-7060 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e7ff943f557f497b3541efe53d82a4 https://doi.org/10.1021/acs.orglett.7b01876 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....d7e7ff943f557f497b3541efe53d82a4 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15237052 15237060 |
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