Oncological outcomes following minimally invasive surgery for pathological N2M0 colorectal cancer: A propensity score‐matched analysis
| العنوان: | Oncological outcomes following minimally invasive surgery for pathological |
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| المؤلفون: | Toshinori Sueda, Mitsuyoshi Tei, Soichiro Mori, Kentaro Nishida, Yukihiro Yoshikawa, Masatoshi Nomura, Tae Matsumura, Chikato Koga, Hiromichi Miyagaki, Masanori Tsujie, Yusuke Akamaru |
| المصدر: | Asian Journal of Endoscopic Surgery. 15:781-793 |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Treatment Outcome, Rectal Neoplasms, Humans, Minimally Invasive Surgical Procedures, General Medicine, Length of Stay, Propensity Score, Retrospective Studies |
| الوصف: | Whether minimally invasive surgery (MIS) is safe and effective for patients with N2M0 colorectal cancer (CRC) remains controversial. This study aimed to compare short- and long-term outcomes between MIS and open surgery (Open) groups for patients with pathological (p)N2M0 CRC, and evaluate the oncological outcomes of MIS for pN2M0 CRC.We retrospectively analyzed 125 consecutive patients with pN2M0 CRC who underwent curative surgery between 2010 and 2017, using propensity score-matching (PSM) analysis.Median follow-up was 59.4 months. After PSM, we enrolled 68 patients (n = 34 in each group). The conversion rate was 9.6% for the entire patient cohort and 5.9% for the matched cohort. In colon cancer (CC), short-term outcomes were similar between groups. On the other hand, in rectal cancer (RC), estimated blood loss, rate of anastomosis leakage, and length of postsurgical stay were lower in the MIS group than the Open group. R0 resection was achieved in all patients with MIS. No surgical mortality was encountered in any group. No significant differences were found between groups in terms of 3-year local recurrence rate, overall survival, cancer-specific survival, or recurrence-free survival among the entire patient cohort or the matched cohort, regardless of the primary tumor site (CC or RC). Surgical approach (MIS vs Open) had no significant influence on survival outcomes.MIS is a safe and effective option for patients with pN2M0 CRC, with acceptable short- and long-term outcomes comparable to the open approach. MIS can be considered for patients with pN2M0 CRC. |
| تدمد: | 1758-5910 1758-5902 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9201395e9bf2d7f39e9ce57dff71b99 https://doi.org/10.1111/ases.13094 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....d9201395e9bf2d7f39e9ce57dff71b99 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17585910 17585902 |
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