Malignancy in Solitary Thyroid Nodules: Evaluation of Risk Factors
| العنوان: | Malignancy in Solitary Thyroid Nodules: Evaluation of Risk Factors |
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| المؤلفون: | Bahadır Çetin, Kemal Beksac, Bülent Aksel, Mehmet Ali Gulcelik, Gokhan Giray Akgul, Uğur Berberoğlu, Lutfi Dogan, Osman Uyar |
| المصدر: | Oncology Research and Treatment. 40:360-363 |
| بيانات النشر: | S. Karger AG, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Male, Thyroid nodules, Cancer Research, medicine.medical_specialty, Adolescent, Turkey, medicine.medical_treatment, Malignancy, Risk Assessment, Sensitivity and Specificity, Young Adult, 03 medical and health sciences, Age Distribution, 0302 clinical medicine, Vascularity, Cervical lymphadenopathy, Prevalence, Humans, Medicine, Thyroid Nodule, 030212 general & internal medicine, Sex Distribution, Risk factor, Thyroid cancer, Aged, Proportional Hazards Models, business.industry, Thyroidectomy, Reproducibility of Results, Nodule (medicine), Hematology, Middle Aged, Prognosis, medicine.disease, Survival Rate, Oncology, 030220 oncology & carcinogenesis, Female, Radiology, Sentinel Lymph Node, medicine.symptom, business |
| الوصف: | Background: The aim of the present study was to evaluate patients with suspicious solitary nodules undergoing bilateral total thyroidectomy for the presence of malignancy. Patients and Methods: 141 patients with true solitary thyroid nodules who underwent bilateral total thyroidectomy at the Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital between 2008 and 2013 were retrospectively evaluated. Parameters including demographics, ultrasonographic findings, and laboratory values were analyzed. Results: When the final pathology results were evaluated, malignancy was found in 52/141 (36.9%) patients. 49 (94.2%) of these lesions were papillary carcinoma. Colloidal nodules accounted for 30.3% of all benign cases. Nodular irregularity, increased vascularity, microcalcification, and central/lateral lymphadenopathy significantly increased the risk of malignancy. Among these factors, increased vascularity was the most important risk factor and microcalcification the second. Nodule size did not affect the risk of malignancy. Conclusion: Irregular borders, microcalcification, increased vascularity, and detection of cervical lymphadenopathy were found to be correlated with malignancy in solitary nodules. |
| تدمد: | 2296-5262 2296-5270 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9da99517d0ba44b9fedb8337b3b945e https://doi.org/10.1159/000464409 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....d9da99517d0ba44b9fedb8337b3b945e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22965262 22965270 |
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