Surface-Enhanced Raman Spectroscopy of Fluid-Supported Lipid Bilayers
| العنوان: | Surface-Enhanced Raman Spectroscopy of Fluid-Supported Lipid Bilayers |
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| المؤلفون: | Bruce E. Brinson, William Lum, Emilie Ringe, Zohre Gorunmez, Laura B. Sagle, Ian Bruzas |
| المصدر: | ACS Applied Materials & Interfaces. 11:33442-33451 |
| بيانات النشر: | American Chemical Society (ACS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Materials science, Bilayer, Substrate (chemistry), Nanotechnology, Biological membrane, 02 engineering and technology, Surface-enhanced Raman spectroscopy, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, symbols.namesake, Membrane, Ellipsometry, symbols, General Materials Science, 0210 nano-technology, Lipid bilayer, Raman spectroscopy |
| الوصف: | Supported lipid bilayers are essential model systems for studying biological membranes and for membrane-based sensor development. Surface-enhanced Raman spectroscopy (SERS) stands to add considerably to our understanding of the dynamics and interactions of these systems through direct chemical information. Despite this potential, SERS of lipid bilayers is not routinely achieved. Here, we carried out the first measurements of a solid-supported lipid bilayer on a SERS-active substrate and characterized the bilayer using SERS, atomic force microscopy, surface plasmon resonance spectroscopy, ellipsometry, and fluorescence recovery after photobleaching (FRAP). The creation of a fluid, SERS-active supported lipid bilayer was accomplished through use of a novel silica-coated silver film-over-nanosphere substrate. These substrates offer a powerful new platform to couple common surface techniques that are challenging on the nanoscale, for example, ellipsometry and FRAP, with SERS for studying biological membranes and their dynamics. |
| تدمد: | 1944-8252 1944-8244 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f5d18e2e06497549d86235be1c9aa7 https://doi.org/10.1021/acsami.9b09988 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....d9f5d18e2e06497549d86235be1c9aa7 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 19448252 19448244 |
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