Myocardial involvement in Behçet’s disease may be higher in patients with Neuro-Behçet’s disease: a speckle tracking echocardiographic study
| العنوان: | Myocardial involvement in Behçet’s disease may be higher in patients with Neuro-Behçet’s disease: a speckle tracking echocardiographic study |
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| المؤلفون: | Selen Ucem, Ipek Midi, Nurten Sayar, Esin Engin, Seda Kutlug Agackiran, Beste Özben Sadıç, Murat Sunbul, Haner Direskeneli, Fatma Alibaz-Oner |
| المصدر: | Acta Cardiologica. 77:515-523 |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Adult, medicine.medical_specialty, Heart Ventricles, Speckle tracking echocardiography, Behcet's disease, Disease, Ventricular Function, Left, Ventricular Dysfunction, Left, Speckle pattern, Internal medicine, medicine, Humans, In patient, Heart Atria, business.industry, Behcet Syndrome, Myocardium, General Medicine, Middle Aged, medicine.disease, eye diseases, stomatognathic diseases, Echocardiography, Cardiology, Female, Neuro-Behçet's disease, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Behcet's disease (BD) may present with life threating complications including neurological and cardiovascular involvement. Neuro-Behcet's disease (NBD) is one of the most important causes of morbidity and mortality in patients with BD. The aim of the present study is to investigate whether patients with NBD are different than BD patients with other manifestations in terms of subclinical myocardial dysfunction.Forty patients with NBD (23 female, mean age: 42.4 ± 9.4 years), 40 patients with BD (9 female, mean age: 39.7 ± 9.0 years) and 40 controls (20 male, mean age: 41.8 ± 6.5 years) were consecutively included in the study. All subjects underwent a transthoracic echocardiography for evaluation of left ventricular (LV) and atrial (LA) functions with two-dimensional (2D) speckle tracking echocardiography (STE).Baseline characteristics, clinical data, LV dimensions, systolic and diastolic functions were all in normal range among the groups. LV global longitudinal strain (LV-GLS) was significantly lower in patients with NBD and BD patients without neurologic involvement compared to controls. LA conduit strain was significantly lower in patients with NBD compared to controls. Patients with both parenchymal NBD and vascular NBD manifestations had significantly lower LV-GLS and LA conduit strain compared to controls. Linear regression analysis demonstrated that among cardiovascular risk factors only presence of NBD was the independent predictor of LV-GLS.BD is associated with impaired LV and LA functions. LV-GLS and LA conduit strains of the patients with NBD were lower. NBD was an independent predictor of LV-GLS, suggesting a link between neurological manifestations and cardiac dysfunction in BD patients. |
| تدمد: | 0373-7934 0001-5385 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5ff4906526160872b4dd2d845542ff https://doi.org/10.1080/00015385.2021.1965354 |
| رقم الأكسشن: | edsair.doi.dedup.....da5ff4906526160872b4dd2d845542ff |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 03737934 00015385 |
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