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Hisataka Fujimoto,1,* Shintaro Ochi,2,* Yasushi Inoue,2 Junichi Kiryu1 1Department of Ophthalmology, Kawasaki Medical School, Kurashiki, 701-0192, Okayama, Japan; 2Inoue Eye Clinic, Tamano, 706-0011, Okayama, Japan*These authors contributed equally to this workCorrespondence: Hisataka FujimotoDepartment of Ophthalmology, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Okayama, Japan, Tel +81-86-462-1111, Fax +81-86-462-1199, Email fujimoto-h@med.kawasaki-m.ac.jpYasushi InoueInoue Eye Clinic, 1-14-31 Uno, Tamano, 706-0011, Okayama, Japan, Tel +81-86-331-1030, Fax +81-86-331-1114, Email inoue@oka.urban.ne.jpPurpose: To evaluate perioperative dry eye (DE) syndrome and meibomian gland (MG) dysfunction parameters associated with cataract surgery-induced DE symptoms.Patients and Methods: This retrospective, single-centered, observational study included 82 eyes of 43 patients without previous subjective DE symptoms, treatment, ocular comorbidities, and previous use of ophthalmic treatment, except for anti-allergic eye drops, who underwent uncomplicated cataract surgery. MG dropout, lid margin abnormality, meibum quality, meibum expressibility, MG orifice obstruction, ocular surface disease index, non-invasive tear break-up time, tear meniscus height, and Schirmer test score were measured at baseline and 1 month postoperatively. Multivariable logistic regression with generalized estimating equation models was used to determine the risk factors for cataract surgery-induced DE symptoms.Results: Twenty-one patients had subjective DE symptoms 1 month following the cataract surgery. Preoperative and postoperative parameters, preoperative upper eyelid MG loss, and female sex (odds ratio [OR] 6.72, P = 0.012; OR 4.20, P = 0.037, respectively) were identified as risk factors for cataract surgery-induced DE symptoms.Conclusion: Ocular parameters, including upper eyelid MG findings at baseline, were considered important in predicting persistent DE symptoms following cataract surgery.Keywords: meibomian gland dysfunction, dry eye syndrome, retrospective, ocular surface disease index |
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