Cyclopropane-Fused N-Heterocycles via Aza-Heck-Triggered C(sp3)–H Functionalization Cascades
| العنوان: | Cyclopropane-Fused N-Heterocycles via Aza-Heck-Triggered C(sp3)–H Functionalization Cascades |
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| المؤلفون: | Changcheng Jing, Benjamin T. Jones, Ross J. Adams, John F. Bower |
| المصدر: | Journal of the American Chemical Society |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Colloid and Surface Chemistry, General Chemistry, Biochemistry, Catalysis |
| الوصف: | Unique examples of aza-Heck-based C(sp3)-H functionalization cascades are described. Under Pd(0)-catalyzed conditions, the aza-Heck-type cyclization of N-(pentafluorobenzoyloxy)carbamates generates alkyl-Pd(II) intermediates that effect C(sp3)-H palladation en route to cyclopropanes. Key factors that control the site selectivity of the cyclopropanation process have been elucidated such that selective access to a wide range of ring- or spiro-fused systems can be achieved. |
| وصف الملف: | application/pdf |
| تدمد: | 1520-5126 0002-7863 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1dac74afd885895abf9beb667aee63 https://doi.org/10.1021/jacs.2c08304 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....db1dac74afd885895abf9beb667aee63 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15205126 00027863 |
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