Non-mumps Viral Parotitis During the 2014–2015 Influenza Season in the United States
| العنوان: | Non-mumps Viral Parotitis During the 2014–2015 Influenza Season in the United States |
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| المؤلفون: | Anna Strain, Mary Anne Jackson, Lori Webber, Jaime Christensen, Lenee Blanton, Thomas Haupt, Lyn Finelli, Kay Radford, Natalie A Kramer, Anna Kocharian, Brett Whitaker, Rebecca J. McNall, John R. Barnes, Jennifer B. Rosen, Jennifer Palm, Melissa A Rolfes, John J Dreisig, Beth M. Isaac, Alexander J. Millman, Pamela Talley, Rebecca Garten, Sara Robinson, Stefanie Cole, Tonya Danz, Karen Martin, George Turabelidze, Jeffrey P. Davis, Daniel Leifer, Peter Shult, Meghan Pearce Weinberg, Erik Reisdorf, Senthilkumar K. Sakthivel, Lisa McHugh, Ruth Lynfield, David E. Wentworth, Michael A. Jhung, Lina I Elbadawi |
| المصدر: | Clinical Infectious Diseases. 67:493-501 |
| بيانات النشر: | Oxford University Press (OUP), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, 0301 basic medicine, Microbiology (medical), Simplexvirus, food.ingredient, Adolescent, viruses, 030106 microbiology, medicine.disease_cause, Article, Virus, Young Adult, 03 medical and health sciences, 0302 clinical medicine, food, Surveys and Questionnaires, Influenza, Human, Sore throat, medicine, Humans, 030212 general & internal medicine, Child, Mumps, Articles and Commentaries, Aged, Aged, 80 and over, business.industry, Infant, Newborn, Infant, Outbreak, Pharyngitis, Cytomegalovirus, Middle Aged, medicine.disease, Virology, United States, Human Parainfluenza Virus, Infectious Diseases, Child, Preschool, Viruses, Female, Seasons, medicine.symptom, business, Parotitis |
| الوصف: | Background During the 2014-2015 US influenza season, 320 cases of non-mumps parotitis (NMP) among residents of 21 states were reported to the Centers for Disease Control and Prevention (CDC). We conducted an epidemiologic and laboratory investigation to determine viral etiologies and clinical features of NMP during this unusually large occurrence. Methods NMP was defined as acute parotitis or other salivary gland swelling of >2 days duration in a person with a mumps- negative laboratory result. Using a standardized questionnaire, we collected demographic and clinical information. Buccal samples were tested at the CDC for selected viruses, including mumps, influenza, human parainfluenza viruses (HPIVs) 1-4, adenoviruses, cytomegalovirus, Epstein-Barr virus (EBV), herpes simplex viruses (HSVs) 1 and 2, and human herpes viruses (HHVs) 6A and 6B. Results Among the 320 patients, 65% were male, median age was 14.5 years (range, 0-90), and 67% reported unilateral parotitis. Commonly reported symptoms included sore throat (55%) and fever (48%). Viruses were detected in 210 (71%) of 294 NMP patients with adequate samples for testing, ≥2 viruses were detected in 37 samples, and 248 total virus detections were made among all samples. These included 156 influenza A(H3N2), 42 HHV6B, 32 EBV, 8 HPIV2, 2 HPIV3, 3 adenovirus, 4 HSV-1, and 1 HSV-2. Influenza A(H3N2), HHV6B, and EBV were the most frequently codetected viruses. Conclusions Our findings suggest that, in addition to mumps, clinicians should consider respiratory viral (influenza) and herpes viral etiologies for parotitis, particularly among patients without epidemiologic links to mumps cases or outbreaks. |
| تدمد: | 1537-6591 1058-4838 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db245dfa129d120a1ed5e04549c5a7be https://doi.org/10.1093/cid/ciy137 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....db245dfa129d120a1ed5e04549c5a7be |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15376591 10584838 |
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