Steroidal alkaloids defence metabolism and plant growth are modulated by the joint action of gibberellin and jasmonate signalling
| العنوان: | Steroidal alkaloids defence metabolism and plant growth are modulated by the joint action of gibberellin and jasmonate signalling |
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| المؤلفون: | Prashant D. Sonawane, Samuel Bocobza, Adam Jozwiak, Varvara Dikaya, Robert C. Schuurink, Jedrzej Szymanski, Himabindu Vasuki, Efrat Almekias-Siegl, Sagit Meir, Andrii Vainer, Sayantan Panda, David Weiss, Asaph Aharoni, Hagai Yasuor, Guy Wizler, Yana Kazachkova, Ashok P. Giri, Avinash Kamble, Hagai Shohat |
| المساهمون: | Plant Physiology (SILS, FNWI) |
| المصدر: | New Phytologist, 233(3), 1220-1237. Wiley-Blackwell |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Physiology, Catabolism, Plant Science, Metabolism, Cyclopentanes, Biology, Gibberellins, Cell biology, Crosstalk (biology), Alkaloids, Solanum lycopersicum, Gene Expression Regulation, Plant, Gibberellin, Jasmonate, Oxylipins, Receptor, Transcription factor, Hormone |
| الوصف: | Steroidal glycoalkaloids (SGAs) are protective metabolites constitutively produced by Solanaceae species. Genes and enzymes generating the vast structural diversity of SGAs have been largely identified. Yet, mechanisms of hormone pathways coordinating defence (jasmonate; JA) and growth (gibberellin; GA) controlling SGAs metabolism remain unclear. We used tomato to decipher the hormonal regulation of SGAs metabolism during growth vs defence tradeoff. This was performed by genetic and biochemical characterisation of different JA and GA pathways components, coupled with in vitro experiments to elucidate the crosstalk between these hormone pathways mediating SGAs metabolism. We discovered that reduced active JA results in decreased SGA production, while low levels of GA or its receptor led to elevated SGA accumulation. We showed that MYC1 and MYC2 transcription factors mediate the JA/GA crosstalk by transcriptional activation of SGA biosynthesis and GA catabolism genes. Furthermore, MYC1 and MYC2 transcriptionally regulate the GA signalling suppressor DELLA that by itself interferes in JA-mediated SGA control by modulating MYC activity through protein-protein interaction. Chemical and fungal pathogen treatments reinforced the concept of JA/GA crosstalk during SGA metabolism. These findings revealed the mechanism of JA/GA interplay in SGA biosynthesis to balance the cost of chemical defence with growth. |
| وصف الملف: | application/pdf |
| تدمد: | 1469-8137 0028-646X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcc548ccd1eedf47aa2953e79de1d53 https://pubmed.ncbi.nlm.nih.gov/34758118 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....dbcc548ccd1eedf47aa2953e79de1d53 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14698137 0028646X |
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