An alternative to a randomised control design for assessing the efficacy and effectiveness of bracing in adolescent idiopathic scoliosis
| العنوان: | An alternative to a randomised control design for assessing the efficacy and effectiveness of bracing in adolescent idiopathic scoliosis |
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| المؤلفون: | Kdk Luk, WY Cheung, Dino Samartzis, I. C. Y. Fu, Daniel Y. T. Fong, Kenneth M.C. Cheung, Michael Kai Tsun To, Eeyl Kuong, K. C. Mak, YW Wong |
| المصدر: | The Bone & Joint Journal. :973-981 |
| بيانات النشر: | British Editorial Society of Bone & Joint Surgery, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Adolescent, Idiopathic scoliosis, law.invention, Cohort Studies, Randomized controlled trial, law, Humans, Medicine, Orthopedics and Sports Medicine, Braces, business.industry, Small sample, Odds ratio, Confidence interval, Brace, Bracing, Treatment Outcome, Scoliosis, Evaluation Studies as Topic, Physical therapy, Feasibility Studies, Female, Surgery, business, Cohort study |
| الوصف: | Randomised controlled trials (RCTs) that assessed the efficacy of bracing for adolescent idiopathic scoliosis have suffered from small sample sizes, low compliance and lack of willingness to participate. The aim of this study was to assess the feasibility of a comprehensive cohort study for evaluating both the efficacy and the effectiveness of bracing in patients with adolescent idiopathic scoliosis. Patients with curves at greater risk of progression were invited to join a randomised controlled trial. Those who declined were given the option to remain in the study and to choose whether they wished to be braced or observed. Of 87 eligible patients (5 boys and 63 girls) identified over one year, 68 (78%) with mean age of 12.5 years (10 to 15) consented to participate, with a mean follow-up of 168 weeks (0 to 290). Of these, 19 (28%) accepted randomisation. Of those who declined randomisation, 18 (37%) chose a brace. Patients who were more satisfied with their image were more likely to choose bracing (Odds Ratio 4.1; 95% confidence interval 1.1 to 15.0; p = 0.035). This comprehensive cohort study design facilitates the assessment of both efficacy and effectiveness of bracing in patients with adolescent idiopathic scoliosis, which is not feasible in a conventional randomised controlled trial. Cite this article: Bone Joint J 2015; 97-B:973–81 |
| تدمد: | 2049-4408 2049-4394 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc39064b9b48ab031e66c9d7af120df8 https://doi.org/10.1302/0301-620x.97b7.35147 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....dc39064b9b48ab031e66c9d7af120df8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20494408 20494394 |
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