Is it Rational to Perform Liver Resection for Patients with Intermediate and Advanced Stages of Hepatocellular Carcinoma?
| العنوان: | Is it Rational to Perform Liver Resection for Patients with Intermediate and Advanced Stages of Hepatocellular Carcinoma? |
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| المؤلفون: | Serdar Topaloglu, Kadir Tomas, Adnan Calik, Mehmet Ozturk, Mehmet Arslan, Hakan Kucukaslan, Sukru Oguz, Hasan Dinç, Feyyaz Ozdemir, Umit Cobanoglu, Erdem Karabulut |
| المصدر: | Scopus-Elsevier |
| بيانات النشر: | SAGE Publications, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Carcinoma, Hepatocellular, Cirrhosis, Adolescent, Turkey, medicine.medical_treatment, Gastroenterology, Disease-Free Survival, Young Adult, Postoperative Complications, Internal medicine, Carcinoma, medicine, Hepatectomy, Humans, Survival rate, Aged, Neoplasm Staging, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, business.industry, Liver Neoplasms, Retrospective cohort study, General Medicine, Middle Aged, Prognosis, medicine.disease, Survival Rate, Hepatocellular carcinoma, Female, business, Viral hepatitis, Liver cancer |
| الوصف: | This study aimed to investigate clinical characteristics of hepatocellular carcinoma and the outcome of our aggressive treatment policy which follows the Barcelona Clinic Liver Cancer (BCLC) guidance. In this study, we retrospectively analyzed data of 102 patients who were treated for hepatocellular carcinoma between January 2007 and October 2016. Male predominance (81.4%) and a median age of 61 years were observed. Cirrhosis was evident in 88.2 per cent of patients. Viral hepatitis (77.5%) was the most common underlying etiology. The majority of our patients (71.6%) were in BCLC B and C stages. Liver resection was performed in 53.4 per cent of patients in those stages. Transarterial chemoembolization was the leading interventional treatment. Overall survival rates at three and five years were 75 per cent and 75 per cent in BCLC 0, 69 per cent and 58 per cent in BCLC A, 50 per cent and 41 per cent in BCLC B, and 11 per cent and 11 per cent in BCLC C, respectively. The BCLC treatment algorithm should consider the role of liver resection also for intermediate stages. |
| تدمد: | 1555-9823 0003-1348 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc95ee46980b39c169874e4d8040ee7f https://doi.org/10.1177/000313482008600427 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....dc95ee46980b39c169874e4d8040ee7f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15559823 00031348 |
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