Comparative in-vitro activity of sparfloxacin and eight other antimicrobial agents against clinical isolates of non-tuberculous mycobacteria
| العنوان: | Comparative in-vitro activity of sparfloxacin and eight other antimicrobial agents against clinical isolates of non-tuberculous mycobacteria |
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| المؤلفون: | R. Blázquez, Teresa Vicente, M. Cotarelo, E. Cercenado, Emilio Bouza, Carlos Sánchez-Carrillo |
| المصدر: | Journal of Antimicrobial Chemotherapy. 37:151-154 |
| بيانات النشر: | Oxford University Press (OUP), 1996. |
| سنة النشر: | 1996 |
| مصطلحات موضوعية: | Microbiology (medical), Microbial Sensitivity Tests, Quinolones, Mycobacterium, Microbiology, Slowly growing Mycobacteria, Anti-Infective Agents, polycyclic compounds, medicine, Tobramycin, heterocyclic compounds, Pharmacology (medical), Antibacterial agent, Pharmacology, biology, business.industry, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Antimicrobial, biology.organism_classification, Anti-Bacterial Agents, Ciprofloxacin, Infectious Diseases, Sparfloxacin, Amikacin, bacteria, business, Fluoroquinolones, medicine.drug |
| الوصف: | The in-vitro activity of sparfloxacin and eight other antimicrobial agents against 64 non-tuberculous mycobacteria (non-MAI) (40 rapidly growing and 24 slowly growing) was compared with those of ciprofloxacin, ofloxacin, amikacin, tobramycin, cefoxitin, imipenem, clarithromycin and doxycycline. Sparfloxacin presented the same activity as ciprofloxacin, being highly active against rapidly growing mycobacteria and showing good in-vitro activity against slowly growing mycobacteria. Amikacin was very active against rapidly growing mycobacteria and clarithromycin presented good activity against all mycobacteria tested. These results suggest that sparfloxacin is a valid agent to be considered in the treatment of Mycobacterium spp. infections. |
| تدمد: | 1460-2091 0305-7453 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcee1e3c89886225a31614a820b41539 https://doi.org/10.1093/jac/37.1.151 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....dcee1e3c89886225a31614a820b41539 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14602091 03057453 |
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