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Comparison of Clinical and Echocardiographic Features of Asymptomatic Patients With Stenotic Bicuspid Versus Tricuspid Aortic Valves

التفاصيل البيبلوغرافية
العنوان: Comparison of Clinical and Echocardiographic Features of Asymptomatic Patients With Stenotic Bicuspid Versus Tricuspid Aortic Valves
المؤلفون: Jamie S.Y. Ho, Kian Keong Poh, Joe Jia-Liang Chua, Chi-Hang Lee, Ruth Chen, Tiong-Cheng Yeo, William Kok-Fai Kong, Nicholas Chew, Hui-Wen Sim, Benjamin Yong-Qiang Tan, Nicholas Ngiam, Ching-Hui Sia
المصدر: The American journal of cardiology. 128
سنة النشر: 2020
مصطلحات موضوعية: Aortic valve, Adult, Male, medicine.medical_specialty, Aortic Diseases, Heart Valve Diseases, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Asymptomatic, Severity of Illness Index, 03 medical and health sciences, 0302 clinical medicine, Bicuspid aortic valve, Bicuspid Aortic Valve Disease, Risk Factors, Internal medicine, Cause of Death, medicine, Humans, 030212 general & internal medicine, Mortality, Asymptomatic Diseases, Aged, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Heart Valve Prosthesis Implantation, Proportional hazards model, business.industry, Age Factors, Retrospective cohort study, Stroke Volume, Stroke volume, Aortic Valve Stenosis, Middle Aged, medicine.disease, Stenosis, medicine.anatomical_structure, Echocardiography, Aortic Valve, Case-Control Studies, Cardiology, Female, Hypertrophy, Left Ventricular, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Dilatation, Pathologic
الوصف: The clinical and imaging differences between bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) patients with medically managed asymptomatic moderate-to-severe aortic stenosis (AS) have not been studied previously. We aim to characterize these differences and their clinical outcomes in this study. A retrospective observational study was conducted on 836 consecutive cases of isolated asymptomatic moderate-to-severe AS, with median follow-up of 3.4 years. Clinical and echocardiographic characteristics were compared between BAV and TAV patients. Subgroup analysis stratified by AS severity were performed. Survival analysis of all-cause mortality was performed using Kaplan-Meier curves and Cox proportional hazards model. Compared to BAV patients, TAV patients were older (76 ± 11 vs 55 ± 16 years, p0.001) and had more co-morbidities including hypertension (78% vs 56%; p0.001), diabetes (41% vs 24%; p0.001), and chronic kidney disease (20% vs 3%; p = 0.001). TAV patients had less severe aortic valve disease than BAV patients, with a higher aortic valve area index (0.71 ± 0.20 cm
تدمد: 1879-1913
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de16d3cbb02ffaef1ac2b17e69ca6d8e
https://pubmed.ncbi.nlm.nih.gov/32534732
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....de16d3cbb02ffaef1ac2b17e69ca6d8e
قاعدة البيانات: OpenAIRE
الوصف
تدمد:18791913