Non-albicans CandidaInfection: An Emerging Threat
| العنوان: | Non-albicans CandidaInfection: An Emerging Threat |
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| المؤلفون: | Sachin C. Deorukhkar, Santosh Saini, Stephen Mathew |
| المصدر: | Interdisciplinary Perspectives on Infectious Diseases Interdisciplinary Perspectives on Infectious Diseases, Vol 2014 (2014) |
| بيانات النشر: | Hindawi Limited, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Microbiology (medical), Antifungal, chemistry.chemical_classification, Article Subject, medicine.drug_class, Virulence, Biology, Isolation (microbiology), biology.organism_classification, Microbiology, lcsh:Infectious and parasitic diseases, Infectious Diseases, Reduced susceptibility, chemistry, Non albicans candida, Virology, medicine, Candida spp, Azole, lcsh:RC109-216, Parasitology, Candida albicans, Research Article |
| الوصف: | The very nature of infectious diseases has undergone profound changes in the past few decades. Fungi once considered as nonpathogenic or less virulent are now recognized as a primary cause of morbidity and mortality in immunocompromised and severely ill patients.Candidaspp. are among the most common fungal pathogens.Candida albicanswas the predominant cause of candidiasis. However, a shift toward non-albicans Candidaspecies has been recently observed. These non-albicans Candidaspecies demonstrate reduced susceptibility to commonly used antifungal drugs. In the present study, we investigated the prevalence of non-albicans Candidaspp. amongCandidaisolates from various clinical specimens and analysed their virulence factors and antifungal susceptibility profile. A total of 523Candidaspp. were isolated from various clinical specimens. Non-albicans Candidaspecies were the predominant pathogens isolated. Non-albicans Candidaspecies also demonstrated the production of virulence factors once attributed toCandida albicans. Non-albicans Candidademonstrated high resistance to azole group of antifungal agents. Therefore, it can be concluded that non-albicans Candidaspecies have emerged as an important cause of infections. Their isolation from clinical specimen can no longer be ignored as a nonpathogenic isolate nor can it be dismissed as a contaminant. |
| وصف الملف: | text/xhtml |
| تدمد: | 1687-7098 1687-708X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de47f88e5b3e6749d720bbb19228f496 https://doi.org/10.1155/2014/615958 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....de47f88e5b3e6749d720bbb19228f496 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16877098 1687708X |
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