Interactions between Auditory and Vestibular Modalities during Stimulation with a Combined Vestibular and Cochlear Prosthesis
| العنوان: | Interactions between Auditory and Vestibular Modalities during Stimulation with a Combined Vestibular and Cochlear Prosthesis |
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| المؤلفون: | Brenda Rebollar, Jay T Rubinstein, James O. Phillips, Amy Nowack, Leo Ling |
| المصدر: | Audiology and Neurotology. 25:96-108 |
| بيانات النشر: | S. Karger AG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Physiology, Hearing Loss, Sensorineural, medicine.medical_treatment, Stimulation, Sensory system, Nystagmus, Audiology, 03 medical and health sciences, Speech and Hearing, 0302 clinical medicine, Stimulus modality, Hearing, Cochlear implant, Sensation, otorhinolaryngologic diseases, medicine, Humans, 030223 otorhinolaryngology, Postural Balance, Vestibular system, Original Paper, Semicircular canal, business.industry, Hearing Tests, Middle Aged, Cochlear Implantation, Semicircular Canals, Sensory Systems, Cochlea, Cochlear Implants, Treatment Outcome, medicine.anatomical_structure, Vestibular Diseases, Otorhinolaryngology, Auditory Perception, Female, Vestibule, Labyrinth, sense organs, medicine.symptom, business, 030217 neurology & neurosurgery |
| الوصف: | Background: A combined vestibular and cochlear prosthesis may restore hearing and balance to patients who have lost both. To do so, the device should activate each sensory system independently. Objectives: In this study, we quantify auditory and vestibular interactions during interleaved stimulation with a combined 16-channel cochlear and 6-channel vestibular prosthesis in human subjects with both hearing and vestibular loss. Methods: Three human subjects were implanted with a combined vestibular and cochlear implant. All subjects had severe-to-profound deafness in the implanted ear. We provided combined stimulation of the cochlear and vestibular arrays and looked for interactions between these separate inputs. Our main outcome measures were electrically evoked slow-phase eye velocities during nystagmus elicited by brief trains of biphasic pulse stimulation of the vestibular end organs with and without concurrent stimulation of the cochlea, and Likert scale assessments of perceived loudness and pitch during stimulation of the cochlea, with and without concurrent stimulation of the vestibular ampullae. Results: All subjects had no auditory sensation resulting from semicircular canal stimulation alone, and no sensation of motion or slow-phase eye movement resulting from cochlear stimulation alone. However, interleaved cochlear stimulation did produce changes in the slow-phase eye velocities elicited by electrical stimulation. Similarly, interleaved semicircular canal stimulation did elicit changes in the perceived pitch and loudness resulting from stimulation at multiple sites in the cochlea. Conclusions: There are significant interactions between different sensory modalities during stimulation with a combined vestibular and cochlear prosthesis. Such interactions present potential challenges for stimulation strategies to simultaneously restore auditory and vestibular function with such an implant. |
| تدمد: | 1421-9700 1420-3030 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df08cfc37272a20bb15a79bc63611fae https://doi.org/10.1159/000503846 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....df08cfc37272a20bb15a79bc63611fae |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219700 14203030 |
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