Hydrocephalus in a Patient with Alzheimer's Disease
| العنوان: | Hydrocephalus in a Patient with Alzheimer's Disease |
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| المؤلفون: | Young Ho Park, SangHak Yi, Min Ju Kang, SangYun Kim |
| المصدر: | Dementia and Neurocognitive Disorders |
| بيانات النشر: | Korean Dementia Association, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, Amyloid, business.industry, Case Report, medicine.disease, Comorbidity, 030218 nuclear medicine & medical imaging, Hydrocephalus, Shunt (medical), 03 medical and health sciences, 0302 clinical medicine, Normal pressure hydrocephalus, Alzheimer Disease, Internal medicine, Posterior cingulate, medicine, Etiology, Cardiology, Dementia, Alzheimer's disease, business, Letter to the Editor, 030217 neurology & neurosurgery |
| الوصف: | Background Normal pressure hydrocephalus (NPH) is an etiology of dementia that is reversible following cerebrospinal fluid shunt placement, however, surgical intervention not always clinically effective and the respons to shunt therapy is poorly understood. Furthermore, NPH is a source of comorbidity in diseases with neurodegenerative pathology, such as Alzheimer's disease (AD). Case report A 61-year-old woman presented to the neurology clinic with progressive gait difficulties and cognitive impairment over five years. Nine years after ventriculoperitoneal (VP) shunt treatment, the patient began to experience frequent falls. There was no improvement in clinical symptoms after the alteration of valve pressure on the VP shunt. An 18F-florbetaben amyloid positron emission tomography scan showed increased diffusion uptake over the bilateral cortices, precuneus, and posterior cingulate cortex. Conclusions The patient of NPH was unresponsive to shunt therapy due to the development of AD. |
| اللغة: | English |
| تدمد: | 2384-0757 1738-1495 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfad8d3b5c2d94a6d08536dddfad791d http://europepmc.org/articles/PMC6427995 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....dfad8d3b5c2d94a6d08536dddfad791d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23840757 17381495 |
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