Clinical characteristics of Egyptian male patients with COVID‐19 acute respiratory distress syndrome
| العنوان: | Clinical characteristics of Egyptian male patients with COVID‐19 acute respiratory distress syndrome |
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| المؤلفون: | Essam A. Hassan, Mahmoud A F Khalil, Ahmed S. Doghish, Mona I. Ahmed, Eman Mahmoud, Walid F. Elkhatib, Ahmed F. Elkhateeb |
| المصدر: | PLoS ONE PLoS ONE, Vol 16, Iss 4, p e0249346 (2021) |
| بيانات النشر: | Public Library of Science, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | ARDS, Viral Diseases, Critical Care and Emergency Medicine, Pulmonology, Physiology, 030204 cardiovascular system & hematology, Gastroenterology, Biochemistry, Monocytes, chemistry.chemical_compound, White Blood Cells, 0302 clinical medicine, Medical Conditions, Animal Cells, Medicine and Health Sciences, Platelet, 030212 general & internal medicine, Lymphocytes, Acute Respiratory Distress Syndrome, Multidisciplinary, biology, Total Cell Counting, C-Reactive Proteins, Body Fluids, medicine.anatomical_structure, Infectious Diseases, Blood, Medicine, Cellular Types, Anatomy, Research Article, medicine.medical_specialty, Science, Immune Cells, Immunology, Cell Enumeration Techniques, Research and Analysis Methods, 03 medical and health sciences, Respiratory Disorders, Respiratory Failure, Internal medicine, Lactate dehydrogenase, Severity of illness, medicine, Creatinine, Ferritin, Blood Cells, business.industry, Monocyte, Biology and Life Sciences, Proteins, Protein Complexes, Covid 19, Cell Biology, medicine.disease, Blood Counts, chemistry, biology.protein, Hemoglobin, business |
| الوصف: | Background Coronavirus disease 2019 (COVID-19) is a serious illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and in severe cases associated with acute respiratory distress syndrome (ARDS). Objective To describe the clinical characteristics of patients with ARDS-COVID-19. Materials and methods This study involved 197 male Egyptian participants, among them111 COVID-19 patients presented with ARDS, 60 COVID-19 patients presented with non-ARDS, and 26 Non-COVID-19 patients. We reported the analysis results of clinical and laboratory information, including blood routine tests, blood biochemistry parameters [aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine and C‐reactive protein (CRP)], thrombotic activity (D‐dimer) and serum ferritin and lactate dehydrogenase (LDH). Results The levels of hemoglobin, AST, creatinine, monocyte count, monocyte %, RBC count, TLC, and platelet count were not significantly different among the groups. The lymphopenia and increased CRP, ALT, D-dimer, ferritin, and LDH were observed in patients with ARDS-COVID-19. Conclusion COVID-19 patients with ARDS presented with lymphopenia, increased thrombotic activity, increased CRP, LDH, and ferritin levels. The results revealed that CRP, D-dimer, LDH levels, and lymphopenia have a significant association with the COVID-19 severity and can be used as biomarkers to predict the disease severity. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca5f89f258826fdbf1af8d73e409c6 http://europepmc.org/articles/PMC8051763 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....dfca5f89f258826fdbf1af8d73e409c6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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