Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials
| العنوان: | Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials |
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| المؤلفون: | Noëlle Cardinaud, Francine Fontaine, Marie Paule Bonceour Martel, Danièle Begorre, Claire Vinel, Dominique Dubois, Serge Bordes, Charlotte Dupuy, Jean-François Dartigues, Lars Bäckman, Marie-Laure Pader, Colette Blatge, Jacques Touchon, Julien Delrieu, Karim Bennys, Miia Kivipelto, Pierre Payoux, Christian Vincent, Ileana Desormais, Françoise Hugon, Isabelle Saulnier, Michèle Allard, Pascale Olivier-Abbal, Patrick Manckoundia, Audrey Gabelle, Yannick Gasnier, Olivier Rouaud, Christine Malick-Loiseau, Carole Badufle, Christian Carpuat, Sophie Marilier, Sophie Peiffer, Stéphane Chanalet, Riitta Antikainen, Jean-Pierre Salles, Stéphanie Roth, Catherine Burdet, Pierre Livet, Nadège Barro-Belaygues, François Cotton, Tiia Ngandu, Pim van Gool, Alexandra Foubert, Eric P. Moll van Charante, Khaled Khales, Pierre-Jean Ousset, Hilkka Soininen, Valérie Faure, Sandrine Andrieu, Corinne Costes, Marie-Noelle-Cuffi, Frédéric Ricolfi, Pascale Rebaudet, Samira Misbah El Idrissi, Céline Caillaud, Marie Chupin, Alain Pesce, Françoise Lala, N. Costa, Emeline Combrouze, Carol Brayne, Bertrand Fougère, Michel Zanca, H. Villars, Sebastien Gonfrier, Fabrice Bonneville, Lynda Touati, Sandrine Cerda, Katri Hemio, Esko Levälahti, Jacques Darcourt, Philippe Robert, Christophe Morin, Brigitte Gilbert, Alain Bonafe, Catherine Faisant, Jacques Monteil, Lawrence Bories, Bram van de Groep, Edo Richard, Gabor Abellan van Kan, Valérie Quipourt, Marc Bonnefoy, Françoise Desclaux, Kristelle Sudres, Thierry Voisin, Timo E. Strandberg, Yves Rolland, Evelyne Franon, Susan Jongstra, Anna Stigsdotter-Neely, Marie-France Basset, Thierry Dantoine, Laurent Molinier, Tiina Laatikainen, Audrey Zueras, Jean-François Lefebvre, Claire Gédéon, Christelle Cantet, Jean-Pierre Clément, Jean-François Mangin, Aurélia Romano, François Chollet, Tuomo Hänninen, Yannick Meiller, Marie-Agnès Picat, Satu Havulinna, Tessa van Middelaar, Jenni Lehtisalo, Isabelle Marcet, Stéphanie Willebois, Christophe Cognard, Hélène Derumeaux, Cécile Pays, Laurence Bernard-Bourzeix, Sylvie Belleville, Anne Hitzel, Cathrien Beishuizen, Ali Bouhayia, Sylvie Chaillou, Bruno Lapoujade, Franck Le Duff, Bruno Vellas, Michael Li Yung Tong, Marieke P. Hoevenaar-Blom, Cecilia Marelli, Rainer Rauramaa, Flavien Terracol, Marko Gronholm, Fleur Delva, Mariagnese Barbera, Sandrine Louchart, Isabelle Carrié, Lauréane Brigitte, Alina Solomon, Bertrand Perret, Claire Gervais, Jaakko Tuomilehto, Carole Dufouil, Sherry L. Willis, Lennard L. van Wanrooij, Cécile Laubarie-Mouret, Nicolas Lebrun, Pierre Skolil, Francesca Mangiasche, Stéphane Lehéricy, Sophie Guyonnet, Jaana Lindström, Evelyne Cazaban-Campistron, Markku Peltonen, Antti Jula, Juliette Guillemont, Nicola Coley |
| المساهمون: | Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Karolinska Institutet [Stockholm], University of Helsinki, Faculty of Health Sciences [UEF, Kuopio, Finland], University of Eastern Finland, Vrije Universiteit Amsterdam [Amsterdam] (VU), Nijmegen Medical Centre [Nijmegen], Centre d'investigation clinique de Toulouse (CIC 1436), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), General practice, Public and occupational health, ACS - Diabetes & metabolism, APH - Health Behaviors & Chronic Diseases, APH - Personalized Medicine, APH - Aging & Later Life, Graduate School, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CCSD, Accord Elsevier, Department of Public Health, Oral and Maxillofacial Surgery, Department of Medicine, Timo Strandberg / Principal Investigator, HUS Internal Medicine and Rehabilitation |
| المصدر: | Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2019, 15 (6), pp.729-741. ⟨10.1016/j.jalz.2019.03.005⟩ Alzheimer s & dementia, 15(6), 729-741. Elsevier Inc. Alzheimer's & Dementia, 15, 729-741 Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019, 15 (6), pp.729-741. ⟨10.1016/j.jalz.2019.03.005⟩ Alzheimer's & Dementia, 15, 6, pp. 729-741 |
| بيانات النشر: | HAL CCSD, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Epidemiology, LIFE-STYLE INTERVENTIONS, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, Psychological intervention, 3124 Neurology and psychiatry, Trial, 0302 clinical medicine, Risk Factors, Outcome Assessment, Health Care, 030212 general & internal medicine, PREDICTORS, Cognitive impairment, Finland, Depression (differential diagnoses), Clinical Trials as Topic, Health Policy, DEPRESSION, Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], Cognitive training, Exercise Therapy, 3. Good health, ALZHEIMERS-DISEASE, Psychiatry and Mental health, Female, medicine.medical_specialty, DISABILITY FINGER, Physical activity, Intervention, Placebo, EXERCISE ADHERENCE, 03 medical and health sciences, Cellular and Molecular Neuroscience, Developmental Neuroscience, Intervention (counseling), Fatty Acids, Omega-3, medicine, Humans, Dementia, OLDER-ADULTS, Life Style, Aged, Cognitive Behavioral Therapy, business.industry, Prevention, [SCCO.NEUR]Cognitive science/Neuroscience, [SCCO.NEUR] Cognitive science/Neuroscience, 3112 Neurosciences, COGNITIVE IMPAIRMENT, medicine.disease, Multidomain, FINNISH GERIATRIC INTERVENTION, PHYSICAL-ACTIVITY, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Adherence, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, Physical therapy, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Neurology (clinical), Geriatrics and Gerontology, business, 030217 neurology & neurosurgery |
| الوصف: | Introduction: Multidomain interventions, targeting multiple risk factors simultaneously, could be effective dementia prevention strategies, but may be burdensome and not universally acceptable. Methods: We studied adherence rates and predictors in the Finnish Geriatric Intervevntion Study to Prevent Cognitive Impairment and Disability and Multidomain Alzheimer Preventive Trial prevention trials, for all intervention components (separately and simultaneously). Finnish Geriatric Intervevntion Study to Prevent Cognitive Impairment and Disability participants received a 2-year multidomain lifestyle intervention (physical training, cognitive training, nutritional counseling, and cardiovascular monitoring). Multidomain Alzheimer Preventive Trial participants received a 3-year multidomain lifestyle intervention (cognitive training, physical activity counseling, and nutritional counseling) with either an omega-3 supplement or placebo. Results: Adherence decreased with increasing intervention complexity and intensity: it was highest for cardiovascular monitoring, nutritional counseling, and the omega-3 supplement, and lowest for unsupervised computer-based cognitive training. The most consistent baseline predictors of adherence were smoking and depressive symptoms. Discussion: Reducing participant burden, while ensuring that technological tools are suitable for older individuals, maintaining face-to-face contacts, and taking into account participant characteristics may increase adherence in future trials. (C) 2019 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2352-8729 1552-5260 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd80b167ec15f68a6464ea2ea5104d9 https://hal.umontpellier.fr/hal-02861724/document |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....dfd80b167ec15f68a6464ea2ea5104d9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23528729 15525260 |
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