Prevalence and Predictors of Postdischarge Antibiotic Use Following Mastectomy
| العنوان: | Prevalence and Predictors of Postdischarge Antibiotic Use Following Mastectomy |
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| المؤلفون: | Victoria J. Fraser, David K. Warren, Anna E. Wallace, Katelin B. Nickel, Margaret A. Olsen |
| المصدر: | Infection Control & Hospital Epidemiology. 38:1048-1054 |
| بيانات النشر: | Cambridge University Press (CUP), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Microbiology (medical), medicine.medical_specialty, Adolescent, Databases, Factual, Epidemiology, medicine.drug_class, Mammaplasty, medicine.medical_treatment, Population, Antibiotics, 030230 surgery, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Prevalence, medicine, Humans, Surgical Wound Infection, Antibiotic prophylaxis, education, Mastectomy, Retrospective Studies, education.field_of_study, Insurance, Health, business.industry, Retrospective cohort study, Antibiotic Prophylaxis, Middle Aged, Drug Utilization, United States, Anti-Bacterial Agents, Cephalosporins, Infectious Diseases, 030220 oncology & carcinogenesis, Relative risk, Female, business, Breast reconstruction, Fluoroquinolones |
| الوصف: | OBJECTIVESurvey results suggest that prolonged administration of prophylactic antibiotics is common after mastectomy with reconstruction. We determined utilization, predictors, and outcomes of postdischarge prophylactic antibiotics after mastectomy with or without immediate breast reconstruction.DESIGNRetrospective cohort.PATIENTSCommercially insured women aged 18–64 years coded for mastectomy from January 2004 to December 2011 were included in the study. Women with a preexisting wound complication or septicemia were excluded.METHODSPredictors of prophylactic antibiotics within 5 days after discharge were identified in women with 1 year of prior insurance enrollment; relative risks (RR) were calculated using generalized estimating equations.RESULTSOverall, 12,501 mastectomy procedures were identified; immediate reconstruction was performed in 7,912 of these procedures (63.3%). Postdischarge prophylactic antibiotics were used in 4,439 procedures (56.1%) with immediate reconstruction and 1,053 procedures (22.9%) without immediate reconstruction (PP>.05).CONCLUSIONSProphylactic postdischarge antibiotics are commonly prescribed after mastectomy; immediate reconstruction is the strongest predictor. Stewardship efforts in this population to limit continuation of prophylactic antibiotics after discharge are needed to limit antimicrobial resistance.Infect Control Hosp Epidemiol2017;38:1048–1054 |
| تدمد: | 1559-6834 0899-823X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01f2cb32801abe583509668954dc298 https://doi.org/10.1017/ice.2017.128 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e01f2cb32801abe583509668954dc298 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15596834 0899823X |
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