Absorption of methylmercury from hair ingested by rats

التفاصيل البيبلوغرافية
العنوان: Absorption of methylmercury from hair ingested by rats
المؤلفون: Robert L. Dedrick, Fred F. Farris
المصدر: Life sciences. 53(12)
سنة النشر: 1993
مصطلحات موضوعية: MERCURE, Male, Metabolite, chemistry.chemical_element, Kidney, General Biochemistry, Genetics and Molecular Biology, Intestinal absorption, Absorption, Rats, Sprague-Dawley, chemistry.chemical_compound, Animal science, Ingestion, Animals, General Pharmacology, Toxicology and Pharmaceutics, Methylmercury, Feces, Mercury Radioisotopes, Chemistry, Radiochemistry, General Medicine, Mercury, Methylmercury Compounds, Mercury (element), Bioavailability, Rats, Liver, Hair
الوصف: Hair taken from rats dosed with 203 Hg-labeled methylmercury was fed to previously untreated rats in order to determine if the organo-mercurial was available for release from the hair matrix within the gut lumen and for subsequent systematic absorption. Cumulative fecal excretion data were consistent with an absorption of about 80% of the ingested methylmercury. The relative amounts of methylmercury and of its metabolite, inorganic mercury, in the feces indicated that the percentage of the parent compound released from hair within the intestine equaled or exceeded the estimated bioavailability. Radioactivity in tissues of animals killed 42 hr following hair consumption confirmed that mercury absorption had occured.
تدمد: 0024-3205
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06319faf5620648afbc8698142cb2c7
https://pubmed.ncbi.nlm.nih.gov/8361326
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....e06319faf5620648afbc8698142cb2c7
قاعدة البيانات: OpenAIRE