Hypoglycemia in patients with type 2 diabetes using concomitant exenatide BID and long-acting insulin therapy
| العنوان: | Hypoglycemia in patients with type 2 diabetes using concomitant exenatide BID and long-acting insulin therapy |
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| المؤلفون: | Manjiri Pawaskar, Rolin L Wade, Amy Blickensderfer, Ralph Quimbo, Byron J. Hoogwerf |
| المصدر: | Journal of Medical Economics. 14:705-708 |
| بيانات النشر: | Informa Healthcare, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Long acting insulin, medicine.medical_treatment, Health Behavior, Comorbidity, Type 2 diabetes, Hypoglycemia, Insulin dose, Insurance Claim Review, Internal medicine, medicine, Humans, Hypoglycemic Agents, In patient, Aged, Retrospective Studies, Aged, 80 and over, Venoms, business.industry, Health Policy, Insulin, Middle Aged, medicine.disease, Insulin, Long-Acting, Endocrinology, Diabetes Mellitus, Type 2, Concomitant, Exenatide, Drug Therapy, Combination, Female, Peptides, business, medicine.drug |
| الوصف: | The objective of this study was to examine the frequency of hypoglycemia among patients with type 2 diabetes who had concomitantly used exenatide BID (exenatide) and long-acting insulin and continued this combination vs those who continued long-acting insulin alone.Retrospective analyses, using a large managed care database, were used to estimate the frequency of hypoglycemia (episodes/patient/6 months) for patients who concomitantly used exenatide and long-acting insulin during a 6-month follow-up period.From among 2082 patients on concomitant exenatide and long-acting insulin, those who continued this combination (n=472) had a lower frequency of hypoglycemia compared to those who remained on long-acting insulin alone (n=312) (0.03 ± 1.9 vs 0.10 ± 1.01 [episodes/patient/6 months]; p0.0001).Only hypoglycemia that required medical intervention (coded for hypoglycemia) was captured. The study could not evaluate any association between insulin dose titration and hypoglycemia or examine other outcomes such as HbA1c, weight, and body mass index, due to lack of data availability.Patients who concomitantly used exenatide BID and long-acting insulin experienced a lower rate of hypoglycemia. |
| تدمد: | 1941-837X 1369-6998 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08a6148904a014f74caed5aa9265e7c https://doi.org/10.3111/13696998.2011.613505 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e08a6148904a014f74caed5aa9265e7c |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 1941837X 13696998 |
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