Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference
| العنوان: | Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference |
|---|---|
| المؤلفون: | Jason Gotlib, Bruce S. Bochner, Cem Akin, Anne Maitland, K. Frank Austen, Mohamad Jawhar, Hanneke C. Kluin-Nelemans, Peter Valent, Stephen J. Galli, Michael W. Deininger, Joseph H. Butterfield, Dean D. Metcalfe, Melody C. Carter, Daniel F. Dwyer, Hans-Peter Horny, Catherine R. Weiler, Lawrence B. Schwartz, Theoharis C. Theoharides, Mariana Castells, Matthew J. Hamilton, Hanneke Oude Elberink, Tracy I. George, Jonathan J. Lyons, Deepti Radia, Wolfgang R. Sperr, Patrizia Bonadonna, Celalettin Ustun, Alberto Orfao, Michel Arock |
| المساهمون: | National Institutes of Health (US), Charles and Ann Johnson Foundation, National Institute of Allergy and Infectious Diseases (US), American Academy of Allergy Asthma and Immunology, Austrian Science Fund |
| المصدر: | J Allergy Clin Immunol Digital.CSIC. Repositorio Institucional del CSIC instname |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Mast cell activation syndrome, BASAL SERUM TRYPTASE, Diagnostic methods, IRRITABLE-BOWEL-SYNDROME, ONSET MASTOCYTOSIS, Immunology, Disease, ACTIVATION SYNDROME, Systemic mastocytosis, CLASSIFICATION, Article, EUROPEAN COMPETENCE NETWORK, Competence (law), 03 medical and health sciences, 0302 clinical medicine, medicine, Immunology and Allergy, Anaphylaxis, Medical education, Cutaneous Mastocytosis, Siglec-8, medicine.disease, Mast cell, CONNECTIVE-TISSUE, 030104 developmental biology, medicine.anatomical_structure, 030228 respiratory system, American Initiative in Mast Cell Diseases (AIM), European Competence Network on Mastocytosis (ECNM), Hereditary alpha-tryptasemia, medicine.symptom, HUMAN EOSINOPHILS, Mast Cell Diseases |
| الوصف: | The American Initiative in Mast Cell Diseases (AIM) held its inaugural investigator conference at Stanford University School of Medicine in May 2019. The overarching goal of this meeting was to establish a Pan-American organization of physicians and scientists with multidisciplinary expertise in mast cell disease. To serve this unmet need, AIM envisions a network where basic, translational, and clinical researchers could establish collaborations with both academia and biopharma to support the development of new diagnostic methods, enhanced understanding of the biology of mast cells in human health and disease, and the testing of novel therapies. In these AIM proceedings, we highlight selected topics relevant to mast cell biology and provide updates regarding the recently described hereditary alpha-tryptasemia. In addition, we discuss the evaluation and treatment of mast cell activation (syndromes), allergy and anaphylaxis in mast cell disorders, and the clinical and biologic heterogeneity of the more indolent forms of mastocytosis. Because mast cell disorders are relatively rare, AIM hopes to achieve a coordination of scientific efforts not only in the Americas but also in Europe by collaborating with the well-established European Competence Network on Mastocytosis. The research reported in this publication was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health (NIH) (award no. R13TR002722 to J.G.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. We thank The Mast Cell Disease Society, Inc (TMS), a national 501c3 nonprofit, for their partnership and support of AIM, for patient-centered research, and for sponsoring international physicians at this inaugural meeting. J.G. expresses gratitude for the support of the Charles and Ann Johnson Foundation, the staff of the Stanford Mastocytosis Center, and the Stanford Cancer Institute Innovation Fund. M.C., J.J.L., and D.D.M. are supported in part by the Division of Intramural Research of the National Institute of Allergy and Infectious Diseases, NIH. D.F.D. is supported by the Asthma and Allergic Diseases Cooperative Research Centers Opportunity Fund (award no. U19AI07053 from the NIH). P.V. has been supported by the Austrian Science Fund (FWF) (grant nos. F4701-B20, F4704-B20, and P32470-B). |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bd05d85527621ff9c71f497ac17fe5 https://europepmc.org/articles/PMC9521380/ |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e0bd05d85527621ff9c71f497ac17fe5 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |