GENCODE reference annotation for the human and mouse genomes
| العنوان: | GENCODE reference annotation for the human and mouse genomes |
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| المؤلفون: | Rory Johnson, Fernando Pozo, Andrew D. Yates, Magali Ruffier, Alexandra Bignell, Anne Parker, Adam Frankish, Osagie G. Izuogu, If Barnes, Jose Manuel Gonzalez, Tomás Di Domenico, Irwin Jungreis, Cristina Sisu, Fergal J. Martin, Anne-Maud Ferreira, Paul R. Muir, Benedict Paten, Matthew P. Hardy, Manolis Kellis, Jacqueline Chrast, Jane E. Loveland, Yan Zhang, Michael L. Tress, Fabio C. P. Navarro, Barbara Uszczynska-Ratajczak, Jonathan M. Mudge, Mark Diekhans, Shamika Mohanan, James C. Wright, Fiona Cunningham, Toby Hunt, Baikang Pei, Jinuri Xu, Tim Hubbard, Julien Lagarde, Roderic Guigó, Alexandre Reymond, Silvia Carbonell Sala, Bianca M. Schmitt, Sarah Donaldson, Mark Gerstein, Jyoti S. Choudhary, Eloise Stapleton, Bronwen Aken, Laura Martinez, Tiago Grego, Ian T. Fiddes, Joel Armstrong, Carlos García Girón, Marie-Marthe Suner, Paul Flicek, Andrew Berry, Irina Sycheva, Thibaut Hourlier, Daniel R. Zerbino |
| المساهمون: | Wellcome Trust, European Molecular Biology Organization, NIH - National Human Genome Research Institute (NHGRI) (Estados Unidos), Swiss National Science Foundation |
| المصدر: | Frankish, Adam; Diekhans, Mark; Ferreira, Anne-Maud; Johnson, Rory Baldwin; Jungreis, Irwin; Loveland, Jane; Mudge, Jonathan M; Sisu, Cristina; Wright, James; Armstrong, Joel; Barnes, If; Berry, Andrew; Bignell, Alexandra; Carbonell Sala, Silvia; Chrast, Jacqueline; Cunningham, Fiona; Di Domenico, Tomás; Donaldson, Sarah; Fiddes, Ian T; García Girón, Carlos; ... (2019). GENCODE reference annotation for the human and mouse genomes. Nucleic acids research, 47(D1), D766-D773. Oxford University Press 10.1093/nar/gky955 <http://dx.doi.org/10.1093/nar/gky955> Repisalud Instituto de Salud Carlos III (ISCIII) Recercat. Dipósit de la Recerca de Catalunya instname Nucleic Acids Research Nucleic acids research, vol. 47, no. D1, pp. D766-D773 |
| بيانات النشر: | Oxford University Press (OUP), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | DNA ELEMENTS, GENES, PROTEINS, DATABASE, 610 Medicine & health, Genomics, Computational biology, Biology, LONG NONCODING RNAS, Genome, Mice, 03 medical and health sciences, Annotation, 0302 clinical medicine, Databases, Genetic, PROGRAM, Genetics, Database Issue, Animals, Humans, Ensembl, 030304 developmental biology, Internet, 0303 health sciences, IDENTIFICATION, Genome, Human, GENCODE, Computational Biology, Genome, Human/genetics, Molecular Sequence Annotation, Pseudogenes/genetics, Software, Gene Annotation, PRINCIPAL, ENCYCLOPEDIA, CATALOG, 3. Good health, ComputingMethodologies_PATTERNRECOGNITION, Human genome, Pseudogenes, 030217 neurology & neurosurgery |
| الوصف: | The accurate identification and description of the genes in the human and mouse genomes is a fundamental requirement for high quality analysis of data informing both genome biology and clinical genomics. Over the last 15 years, the GENCODE consortium has been producing reference quality gene annotations to provide this foundational resource. The GENCODE consortium includes both experimental and computational biology groups who work together to improve and extend the GENCODE gene annotation. Specifically, we generate primary data, create bioinformatics tools and provide analysis to support the work of expert manual gene annotators and automated gene annotation pipelines. In addition, manual and computational annotation workflows use any and all publicly available data and analysis, along with the research literature to identify and characterise gene loci to the highest standard. GENCODE gene annotations are accessible via the Ensembl and UCSC Genome Browsers, the Ensembl FTP site, Ensembl Biomart, Ensembl Perl and REST APIs as well as https://www.gencodegenes.org. We thank Tim Hubbard and Jennifer Harrow for their lead- ership in the GENCODE project from 2003-2016 as well as all groups and group members involved in the GENCODE project since its inception including the HAVANA manual annotation group formerly at Wellcome Sanger Institute now at EMBL-EBI (founder), the Guigo group at Centre for Genomic Regulation (founder), the Gerstein group at Yale (founder), the Center for Biomolecular Science & En- gineering at UCSC (founder), the Ensembl team at EMBL- EBI (joined 2007), the Kellis group at MIT (joined 2007), the Tress group at CNIO (joined 2007), the Choudhary group formerly at Wellcome Sanger Institute now at Insti- tute of Cancer Research (joined 2012), the Reymond group at University of Lausanne (2003–2017), the Antonarakis group at University of Geneva (2003–2007), the Wei group at Genome Institute of Singapore (2003–2007), the Gin- geras group at Affymetrix Ltd (2003–2007) and the Brent group at Washington University in St. Louis (2007–2012). Sí |
| وصف الملف: | application/pdf |
| تدمد: | 1362-4962 0305-1048 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e181df58a8de4f0403a4a267189a4855 https://doi.org/10.1093/nar/gky955 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e181df58a8de4f0403a4a267189a4855 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13624962 03051048 |
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