Identification of genetic markers forMycobacterium pinnipediithrough genome analysis
| العنوان: | Identification of genetic markers forMycobacterium pinnipediithrough genome analysis |
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| المؤلفون: | Paul Golby, Andrea Peralta, Fabiana Bigi, Javier Nunez-Garcia, Jason Hinds, Stephen V. Gordon, Karina Cynthia Caimi, M. Carmen Garcia-Pelayo, Maria Isabel Romano, Ángel Adrián Cataldi |
| المصدر: | FEMS Microbiology Letters. 248:147-152 |
| بيانات النشر: | Oxford University Press (OUP), 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Genetic Markers, Comparative genomics, Genetics, Mycobacterium bovis, Fur Seals, Genetic Variation, Mycobacterium pinnipedii, Biology, biology.organism_classification, Microbiology, Genome, Mycobacterium, Species Specificity, Mycobacterium tuberculosis complex, Mycobacterium microti, Genetic marker, Genetic variability, Molecular Biology, Genome, Bacterial, Oligonucleotide Array Sequence Analysis |
| الوصف: | Tuberculosis in seals is caused by Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis complex. In this study, we evaluated the extent of genetic variability among Mycobacterium bovis and M. pinnipedii by microarray-based comparative genomics. We identified two deletions that are exclusive to M. pinnipedii: PiD1 that removes the orthologues of the M. tuberculosis genes Rv3530c and Rv3531c, and PiD2 that encompasses genes Rv1977 and Rv1978. Interestingly, a deletion overlapping the previously described RD2 region was identified in some isolates of Mycobacterium microti and further characterised. |
| تدمد: | 1574-6968 0378-1097 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b235fc139d7292ced6355ffdeb78ed https://doi.org/10.1016/j.femsle.2005.05.034 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e1b235fc139d7292ced6355ffdeb78ed |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15746968 03781097 |
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