Impact of age and comorbidity on risk stratification in idiopathic pulmonary arterial hypertension
| العنوان: | Impact of age and comorbidity on risk stratification in idiopathic pulmonary arterial hypertension |
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| المؤلفون: | Magnus Nisell, Jonas Multing, Barbro Kjellström, Clara Hjalmarsson, Göran Rådegran, David Kylhammar, Bengt Rundqvist |
| المصدر: | European Respiratory Journal. 51:1702310 |
| بيانات النشر: | European Respiratory Society (ERS), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Adolescent, Hypertension, Pulmonary, Myocardial Ischemia, MEDLINE, Comorbidity, 030204 cardiovascular system & hematology, Risk Assessment, Young Adult, 03 medical and health sciences, Age Distribution, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Humans, Registries, Renal Insufficiency, Sex Distribution, Young adult, Survival rate, Survival analysis, Aged, Aged, 80 and over, Sweden, business.industry, Middle Aged, medicine.disease, Survival Analysis, Pulmonary hypertension, Survival Rate, 030228 respiratory system, Population study, Female, business, Risk assessment |
| الوصف: | Recent reports from worldwide pulmonary hypertension registries show a new demographic picture for patients with idiopathic pulmonary arterial hypertension (IPAH), with an increasing prevalence among the elderly.We aimed to investigate the effects of age and comorbidity on risk stratification and outcome of patients with incident IPAH.The study population (n=264) was categorised into four age groups: 18–45, 46–64, 65–74 and ≥75 years. Individual risk profiles were determined according to a risk assessment instrument, based on the European Society of Cardiology and the European Respiratory Society guidelines. The change in risk group from baseline to follow-up (median 5 months) and survival were compared across age groups. In the two youngest age groups, a significant number of patients improved (18–45 years, Z= −4.613, pThese findings highlight the importance of age and specific comorbidities as prognostic markers of outcome in addition to established risk assessment algorithms. |
| تدمد: | 1399-3003 0903-1936 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2772cee9c8590f4d49c409f803c3561 https://doi.org/10.1183/13993003.02310-2017 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e2772cee9c8590f4d49c409f803c3561 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13993003 09031936 |
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