Successful Treatment of a Patient with Severe Churg-Strauss Syndrome by a Combination of Pulse Corticosteroids, Pulse Cyclophosphamide, and High-Dose Intravenous Immunoglobulin
| العنوان: | Successful Treatment of a Patient with Severe Churg-Strauss Syndrome by a Combination of Pulse Corticosteroids, Pulse Cyclophosphamide, and High-Dose Intravenous Immunoglobulin |
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| المؤلفون: | Takuo Shibayama, Goro Kimura, Atsuhiko Tada, Mitsuru Munemasa, Kiyoshi Takahashi, Noriko Kawata, Nagio Takigawa, Ryo Soda |
| المصدر: | Journal of Asthma. 42:639-641 |
| بيانات النشر: | Informa UK Limited, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Adult, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Churg-Strauss Syndrome, Severity of Illness Index, Gastroenterology, Hypoxemia, Adrenal Cortex Hormones, Internal medicine, medicine, Humans, Immunologic Factors, Immunology and Allergy, Cyclophosphamide, Asthma, Eosinophil cationic protein, medicine.diagnostic_test, Pulse (signal processing), business.industry, Immunoglobulins, Intravenous, respiratory system, Eosinophil, medicine.disease, respiratory tract diseases, Peripheral neuropathy, Bronchoalveolar lavage, medicine.anatomical_structure, Pediatrics, Perinatology and Child Health, Immunology, Sputum, Drug Therapy, Combination, Female, medicine.symptom, business, Immunosuppressive Agents |
| الوصف: | A 24-year-old woman with a 4-year history of bronchial asthma suffered from bloody sputum, numbness of the extremities, elevated eosinophil count, and hypoxemia. A diagnosis of alveolar hemorrhage was made by bronchoalveolar lavage. Echocardiogram revealed severe hypokinesis of the left ventricular wall. Her respiratory condition deteriorated despite administration of pulse corticosteroids. A second pulse corticosteroids and pulse cyclophosphamide followed by high-dose intravenous immunoglobulin brought about a dramatic improvement of alveolar hemorrhage, cardiac impairment, and peripheral neuropathy. Levels of antimyeloperoxidase-antineutrophil cytoplasmic antibodies, soluble thrombomodulin, soluble interleukin-2 receptor, eosinophil cationic protein were elevated and returned to the normal range in remission. The combination of pulse corticosteroids, pulse cyclophosphamide, and high-dose intravenous immunoglobulin seemed effective for the acute phase of severe Churg-Strauss syndrome. |
| تدمد: | 1532-4303 0277-0903 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29a8450e5a1ed5fd6c34dd57fa396e0 https://doi.org/10.1080/02770900500263822 |
| رقم الأكسشن: | edsair.doi.dedup.....e29a8450e5a1ed5fd6c34dd57fa396e0 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 15324303 02770903 |
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