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Associated liver and multivisceral resections: should we extend the frontiers of resectability?

التفاصيل البيبلوغرافية
العنوان: Associated liver and multivisceral resections: should we extend the frontiers of resectability?
المؤلفون: Guillermo Ojea Quintana, Virginia Cano Busnelli, Martin de Santibañes, Juan Pekolj, Agustin Dietrich, Eduardo de Santibañes
المصدر: Updates in Surgery. 67:11-17
بيانات النشر: Springer Science and Business Media LLC, 2015.
سنة النشر: 2015
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Time Factors, Argentina, Disease, Risk Assessment, Resection, Postoperative Complications, Risk Factors, medicine, Hepatectomy, Humans, Significant risk, Major complication, Aged, Retrospective Studies, business.industry, Incidence, Mortality rate, Liver Neoplasms, Perioperative, Middle Aged, Prognosis, Surgery, Survival Rate, Viscera, Hospital outcomes, Female, Colorectal Neoplasms, business, Major hepatectomy, Follow-Up Studies
الوصف: Combined liver and multivisceral resections (CLMVRs) are rare procedures that demand extensive surgical skills. Few reports have discussed the benefit of these complex procedures and their indications are poorly defined. The aim of the present study is to present short- and long-term results of CLMVRs in primary and metastatic malignancies, including a risk analysis for perioperative morbidity and mortality. A review of our prospective surgical database between November 2007 and August 2013 identified 21 patients who had undergone CLMVRs. Preoperative radiologic evaluation and laboratory data, intraoperative results, hospital outcomes, and long-term follow-up were analyzed. CLMVRs were performed due to metastatic disease from different sites in 17 patients, and due to direct local invasion of the liver in the remaining 4 cases. Major hepatectomy was performed in 7 cases. Morbidity was 57 % and 90-day postoperative mortality was 9 %. Gender and resection of more than 4 organs were found as statistically significant risk factors to develop major complications. Five of 7 patients with 4 or more organs resected presented major complications including mortality (p = 0.026). The overall 1- and 3-year survival rates were 57 and 24 %, respectively. Patients undergoing CLMVRs experience acceptable postoperative morbidity and mortality rates. Surgery should be performed only in carefully selected patients, considering their preoperative comorbidities, and in high-volume centers.
تدمد: 2038-3312
2038-131X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e314bc8ce8077867f43b7dfe6ae0b812
https://doi.org/10.1007/s13304-015-0280-9
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....e314bc8ce8077867f43b7dfe6ae0b812
قاعدة البيانات: OpenAIRE
الوصف
تدمد:20383312
2038131X