Probiotics and prebiotics: potential prevention and therapeutic target for nutritional management of COVID-19?
| العنوان: | Probiotics and prebiotics: potential prevention and therapeutic target for nutritional management of COVID-19? |
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| المؤلفون: | Juliana Gondim de Albuquerque, Maria Helena Araújo de Vasconcelos, Kamila Sabino Batista, Maria Luiza Rolim Bezerra, Jailane de Souza Aquino, Rafael Oliveira Pinheiro, Mariany Bernardino da Silva Barbalho |
| المصدر: | Nutrition Research Reviews |
| بيانات النشر: | Cambridge University Press (CUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Viral infections, medicine.medical_specialty, Abdominal pain, Nutrition and Dietetics, biology, business.industry, Microbiota, Immunity, COVID-19, Medicine (miscellaneous), Review Article, Cochrane Library, Gut flora, biology.organism_classification, medicine.disease, Obesity, Clinical trial, Nutritional status, Diabetes mellitus, medicine, Sore throat, Vomiting, medicine.symptom, Intensive care medicine, business |
| الوصف: | Scientists are working to identify prevention/treatment methods and clinical outcomes of coronavirus disease 2019 (COVID-19). Nutritional status and diet have a major impact on the COVID-19 disease process, mainly because of the bidirectional interaction between gut microbiota and lung, that is, the gut–lung axis. Individuals with inadequate nutritional status have a pre-existing imbalance in the gut microbiota and immunity as seen in obesity, diabetes, hypertension and other chronic diseases. Communication between the gut microbiota and lungs or other organs and systems may trigger worse clinical outcomes in viral respiratory infections. Thus, this review addresses new insights into the use of probiotics and prebiotics as a preventive nutritional strategy in managing respiratory infections such as COVID-19 and highlighting their anti-inflammatory effects against the main signs and symptoms associated with COVID-19. Literature search was performed through PubMed, Cochrane Library, Scopus and Web of Science databases; relevant clinical articles were included. Significant randomised clinical trials suggest that specific probiotics and/or prebiotics reduce diarrhoea, abdominal pain, vomiting, headache, cough, sore throat, fever, and viral infection complications such as acute respiratory distress syndrome. These beneficial effects are linked with modulation of the microbiota, products of microbial metabolism with antiviral activity, and immune-regulatory properties of specific probiotics and prebiotics through Treg cell production and function. There is a need to conduct clinical and pre-clinical trials to assess the combined effect of consuming these components and undergoing current therapies for COVID-19. |
| تدمد: | 1475-2700 0954-4224 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31cb95a28ffd65c6a49f2ec222bf1f4 https://doi.org/10.1017/s0954422421000317 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e31cb95a28ffd65c6a49f2ec222bf1f4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752700 09544224 |
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