Correlation of left ventricular dyssynchrony with myocardial stunning using dual single photon emission computed tomography of 123iodine-β-methyl iodophenyl pentadecanoic acid and 201thallium scintigraphy after reperfusion therapy
| العنوان: | Correlation of left ventricular dyssynchrony with myocardial stunning using dual single photon emission computed tomography of 123iodine-β-methyl iodophenyl pentadecanoic acid and 201thallium scintigraphy after reperfusion therapy |
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| المؤلفون: | Nobuo Yoshimoto, Norinari Honda, Yuji Shimizu, Yoshiaki Maruyama, Nobuyuki Masaki |
| المصدر: | Annals of Nuclear Medicine. 23:799-805 |
| بيانات النشر: | Springer Science and Business Media LLC, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Male, Cardiac function curve, medicine.medical_specialty, Pentadecanoic acid, Single-photon emission computed tomography, Scintigraphy, Ventricular Dysfunction, Left, chemistry.chemical_compound, Reperfusion therapy, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Myocardial infarction, Ventricular dyssynchrony, Myocardial Stunning, Tomography, Emission-Computed, Single-Photon, Myocardial stunning, medicine.diagnostic_test, Iodobenzenes, business.industry, Fatty Acids, General Medicine, Middle Aged, medicine.disease, Thallium Radioisotopes, chemistry, Reperfusion, Cardiology, Feasibility Studies, Female, Nuclear medicine, business |
| الوصف: | Left ventricular (LV) dyssynchrony after reperfusion therapy has been closely examined as a cause of chronic remodeling, but the details have not been clarified. The present study measured LV dyssynchrony appearing immediately after reperfusion therapy using real-time three-dimensional echocardiography (RT-3DE), and assessed the significance of this phenomenon in relation to dual single photon emission computed tomography (SPECT) of (123)iodine beta methyliodophenyl pentadecanoic acid ((123)I-BMIPP) and (201)thallium ((201)Tl).Subjects comprised 58 patients with first-time acute myocardial infarction who received reperfusion therapy and underwent RT-3DE and dual SPECT of (123)I-BMIPP and (201)Tl within two weeks of onset. Two dyssynchrony parameters were measured using RT-3DE in the acute phase and six months later. After evaluating the correlation of these dyssynchrony parameters to resting (201)Tl uptake, (201)Tl washout, (123)I-BMIPP uptake, and (201)Tl-(123)I-BMIPP discrepancy (Tl-BMIPP discrepancy), we compared scintigraphic parameters in the chronic phase between groups with improved dyssynchrony and those without.Acute dyssynchrony exhibited a significant positive correlation to Tl-BMIPP discrepancy and it was significantly increased in the group with improved dyssynchrony in the chronic phase, revealing close relationship between dyssynchrony and Tl-BMIPP discrepancy. Then the subjects were divided into positive Tl-BMIPP discrepancy and negative discrepancy groups, and the parameters of cardiac function were compared between them. In the chronic phase, improved cardiac function was observed in the group with positive Tl-BMIPP discrepancy compared to negative discrepancy.LV dyssynchrony after reperfusion therapy correlates positively with Tl-BMIPP discrepancy, reflecting acute myocardial stunning, in which ventricular contraction improves during the chronic phase. |
| تدمد: | 1864-6433 0914-7187 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e357bf4ffeb7505aa792143a46d5f816 https://doi.org/10.1007/s12149-009-0312-y |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....e357bf4ffeb7505aa792143a46d5f816 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 18646433 09147187 |
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