Epidemiology and Outcomes of Infectious Spondylodiscitis in Hemodialysis Patients
| العنوان: | Epidemiology and Outcomes of Infectious Spondylodiscitis in Hemodialysis Patients |
|---|---|
| المؤلفون: | George Kuo, Ya-Chung Tian, Chao-Yu Chen, Yueh-An Lu, Huang-Kai Kao, Chia-Hui Lee, Wei-Chiao Sun, Yu-Shien Ko, Hsiang-Hao Hsu, Cheng-Chieh Hung, Yu-Jr Lin |
| المصدر: | Spine. 43:869-876 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Methicillin-Resistant Staphylococcus aureus, Spondylodiscitis, medicine.medical_specialty, Discitis, medicine.medical_treatment, 03 medical and health sciences, 0302 clinical medicine, Renal Dialysis, Internal medicine, Epidemiology, Prevalence, medicine, Humans, Orthopedics and Sports Medicine, 030212 general & internal medicine, Survival rate, Dialysis, Aged, Retrospective Studies, Proportional hazards model, business.industry, Incidence, Incidence (epidemiology), Retrospective cohort study, Middle Aged, Staphylococcal Infections, Prognosis, medicine.disease, Female, Neurology (clinical), Hemodialysis, business, 030217 neurology & neurosurgery |
| الوصف: | Study design A retrospective study of patients who were hospitalized for infectious spondylodiscitis over a 13-year period. Objective To elucidate the epidemiology and prognostic factors of infectious spondylodiscitis in hemodialysis (HD) patients and to identify the impact of HD on infectious spondylodiscitis. Summary of background data Only a few case studies of infectious spondylodiscitis in HD patients can be found in the literature. Reports of prognostic factors are limited and patients' outcomes have not been well described. Methods The cases of 1402 patients who were hospitalized for infectious spondylodiscitis over a 13-year period were retrospectively reviewed. Of these, 102 patients on maintenance HD were enrolled in this study. Cox proportional hazard model was used to evaluate the risk factors of mortality and recurrence. Results The 102 enrolled patients had an average age 63.3 ± 11.2 years old and male-to-female ratio of 1:1.04. Back pain was present in 75.5% of patients and the most commonly infected site was the lumbosacral spine. Infection associated with vascular access was identified in 31.4% of patients. The prevalence of dialysis via central venous catheters was higher than prevalent HD patients. Methicillin-resistant Staphylococcus aureus was the most common pathogen, followed coagulase-negative staphylococci. The patients' in-hospital survival rate was 82.4%; their vascular access survival rate was 75.5%; their 1-year survival rate was 78.4%, and their 1-year recurrence rate was 20.2%. Congestive heart failure was associated with an increased 1-year mortality. Other variables exhibited no significant relationship with patients' in-hospital mortality, 1-year mortality or recurrence. Conclusion The characteristics and outcomes of infectious spondylodiscitis in HD patients were elucidated. Most of the demographic and clinical variables, evaluated upon admission, did not predict mortality or recurrence. Level of evidence 3. |
| تدمد: | 1528-1159 0362-2436 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e406baca88b01cacf7108b6a49c69e06 https://doi.org/10.1097/brs.0000000000002443 |
| رقم الأكسشن: | edsair.doi.dedup.....e406baca88b01cacf7108b6a49c69e06 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15281159 03622436 |
|---|