Effect of Subjective and Objective Sleep Quality on Subsequent Peptic Ulcer Recurrence in Older Adults
| العنوان: | Effect of Subjective and Objective Sleep Quality on Subsequent Peptic Ulcer Recurrence in Older Adults |
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| المؤلفون: | Boye Fang, Shuyan Yang, Gengzhen Chen, Huiying Liu, Ruirui Xu |
| المصدر: | Journal of the American Geriatrics Society. 67:1454-1460 |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, Sleep Wake Disorders, China, Peptic Ulcer, medicine.medical_specialty, Multivariate analysis, Disease, Helicobacter Infections, Pittsburgh Sleep Quality Index, Wearable Electronic Devices, 03 medical and health sciences, 0302 clinical medicine, Recurrence, Risk Factors, Internal medicine, medicine, Humans, Endoscopy, Digestive System, Prospective Studies, Aged, Helicobacter pylori, medicine.diagnostic_test, Esophagogastroduodenoscopy, business.industry, Hazard ratio, Sleep in non-human animals, Confidence interval, Female, 030211 gastroenterology & hepatology, Sleep onset latency, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery |
| الوصف: | Objective To examine the effect of subjective and objective sleep quality on subsequent recurrence of peptic ulcer disease (PUD) among older patients after Helicobacter pylori eradication. Setting Eight grade A hospitals in China. Participants Of 1689 older Chinese with H. pylori-infected PUD recruited between January 2011 and October 2014, H. pylori were eradicated and PUD was cleared in 1538 patients by the end of 2014; 1420 of these patients were followed up for up to 36 months. Measurements Using multiple measures at 6-month intervals, PUD recurrence was determined with esophagogastroduodenoscopy. Subjective sleep quality was measured using the Pittsburgh Sleep Quality Index. Objective sleep quality domains were measured using an accelerometer, including sleep onset latency, sleep efficiency, total sleep time, and number of awakenings. Results This study documented a 36-month cumulative PUD recurrence of 8.3% (annual rate = 2.8%). Multivariate analyses showed that participants who reported poorer sleep quality were more likely to experience PUD recurrence during the 36-month follow-up period (hazard ratio [HR] = 1.895; 95% confidence interval [CI] = 1.008-3.327). Regarding objective sleep quality domains, longer sleep onset latency (HR = 1.558; 95% CI = 1.156-2.278) and more nighttime awakenings (HR = 1.697; 95% CI = 1.168-2.665) increased the risk of PUD recurrence. However, a longer total sleeping time protected against PUD recurrence (HR = 0.768; 95% CI = 0.699-0.885). Conclusions Poor sleep quality predicts a greater risk of PUD recurrence. Accurate diagnosis and effective treatments should, therefore, be provided for older adults afflicted with poor sleep, particularly for those who previously had PUD. It is equally important to include sleep assessment as an integral part while dealing with these patients. |
| تدمد: | 1532-5415 0002-8614 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e572585641be6cb24f5cd4caf3c466d7 https://doi.org/10.1111/jgs.15871 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....e572585641be6cb24f5cd4caf3c466d7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15325415 00028614 |
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