Coagulopathies in novel coronavirus (SARS-CoV-2) pandemic: Emerging evidence for hematologists
| العنوان: | Coagulopathies in novel coronavirus (SARS-CoV-2) pandemic: Emerging evidence for hematologists |
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| المؤلفون: | Abeer M. Al-Subaie |
| المصدر: | Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 956-961 (2021) Saudi Journal of Biological Sciences |
| بيانات النشر: | Elsevier BV, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, ARDS, medicine.medical_specialty, VTE, venous thromboembolism, Review, Disease, medicine.disease_cause, Fibrinogen, 01 natural sciences, Asymptomatic, Pathogenesis, 03 medical and health sciences, Internal medicine, medicine, DIC, disseminated intravascular coagulation, Anticoagulant therapy, lcsh:QH301-705.5, Coronavirus, SARS-CoV-2, business.industry, INR, international normalized ratio, COVID-19, Thrombosis, DOACs, direct oral anticoagulants, medicine.disease, LMWH, low molecular weight heparin, 030104 developmental biology, lcsh:Biology (General), medicine.symptom, Disseminated intravascular coagulation (DIC), General Agricultural and Biological Sciences, business, Multiple organ dysfunction syndrome, 010606 plant biology & botany, medicine.drug |
| الوصف: | The coronavirus disease (COVID-19), which is also known as acute respiratory syndrome coronavirus-2 (SARS-CoV2) is a transmissible disease, has phenotypes varying from asymptomatic to Acute Respiratory Distress Syndrome (ARDS) or multiple organ dysfunction syndrome (MODS) and ultimately death in certain cases. Coagulation disorders are being frequently reported amongst these patients and the pathogenesis is still not completely understood. Proposed mechanisms for these coagulopathies comprise a hypercoagulable state with micro- and/or macro-thrombosis in the vessels. A number of changes have been reported or proposed in circulating prothrombotic factors in COVID-19 patients and includes elevation in both factor VIII and fibrinogen, circulating prothrombotic microparticles and hyperviscosity. The COVID-19 patients are showing varied coagulopathies and are at high risk for venous thromboembolism (VTE) which demands an early intervention. This paper reviews the evolving data regarding the evaluation and managing of coagulopathies in patients with COVID-19. |
| تدمد: | 1319-562X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e631f9a498725f1467bb5bfeb73d0842 https://doi.org/10.1016/j.sjbs.2020.11.006 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e631f9a498725f1467bb5bfeb73d0842 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1319562X |
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