Voltage-Driven Flipping of Zwitterionic Artificial Channels in Lipid Bilayers to Rectify Ion Transport

التفاصيل البيبلوغرافية
العنوان: Voltage-Driven Flipping of Zwitterionic Artificial Channels in Lipid Bilayers to Rectify Ion Transport
المؤلفون: Zhan-Ting Li, Jun-Li Hou, Yunxiang Zhang, Yong-Hong Fu, Wenning Wang, Ya-Wei Li, Rongrong Wen, Maohua Yang, Zhao-Jun Yan
المصدر: Journal of the American Chemical Society. 143:11332-11336
بيانات النشر: American Chemical Society (ACS), 2021.
سنة النشر: 2021
مصطلحات موضوعية: Physics::Biological Physics, Ion Transport, Silver, Alamethicin, Molecular Structure, Chemistry, Lipid Bilayers, Electric Conductivity, Silver Compounds, General Chemistry, Condensed Matter::Mesoscopic Systems and Quantum Hall Effect, Biochemistry, Ion Channels, Catalysis, Quantitative Biology::Subcellular Processes, chemistry.chemical_compound, Colloid and Surface Chemistry, Chemical physics, Lipid bilayer, Ion transporter, Computer Science::Information Theory, Voltage, Communication channel
الوصف: We developed a voltage-sensitive artificial transmembrane channel by mimicking the dipolar structure of natural alamethicin channel. The artificial channel featured a zwitterionic structure and could undergo voltage-driven flipping in the lipid bilayers. Importantly, this flipping of the channel could lead to their directional alignment in the bilayers and rectifying behavior for ion transport.
تدمد: 1520-5126
0002-7863
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e681a26b534b4267dc604072bf111709
https://doi.org/10.1021/jacs.1c06000
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....e681a26b534b4267dc604072bf111709
قاعدة البيانات: OpenAIRE