Anti-Müllerian hormone: A function beyond the Müllerian structures
| العنوان: | Anti-Müllerian hormone: A function beyond the Müllerian structures |
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| المؤلفون: | Bertho, S, Neyroud, A S, Brun, T, Jaillard, S, Bonnet, F, Ravel, C |
| المساهمون: | CHU Pontchaillou [Rennes], Institut de recherche en santé, environnement et travail (Irset), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de la Santé et de la Recherche Médicale (INSERM)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université d'Angers (UA), École des Hautes Études en Santé Publique [EHESP] (EHESP), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) |
| المصدر: | Morphologie Morphologie, Elsevier Masson, 2021, ⟨10.1016/j.morpho.2021.11.002⟩ Morphologie, 2021, ⟨10.1016/j.morpho.2021.11.002⟩ |
| بيانات النشر: | Elsevier BV, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Male, Adult, Anti-Mullerian Hormone, endocrine system, 0303 health sciences, urogenital system, [SDV]Life Sciences [q-bio], Brain, Genital tract, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Testis, Humans, Female, Anatomy, Mullerian Ducts, Glycoproteins, Signal Transduction, Cancer, 030304 developmental biology |
| الوصف: | International audience; The anti-Müllerian hormone (AMH) is a heterodimeric glycoprotein belonging to the TGFb superfamily implicated in human embryonic development. This hormone was first described as allowing regression of the epithelial embryonic Müllerian structures in males, which would otherwise differentiate into the uterus and fallopian tubes. It activates a signaling pathway mediated by two transmembrane receptors. Binding of AMH to its receptor induces morphological changes leading to the degeneration of Müllerian ducts. Recently, new data has shown the role played by this hormone on structures other than the genital tract. If testicular AMH expression decreases in humans over the course of a lifetime, synthesis may persist in other tissues in adulthood. The mechanisms underlying its production have been unveiled. The aim of this review is to describe the different pathways in which AMH has been identified and plays a pivotal role. |
| تدمد: | 1286-0115 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a7ddfab353d0ff28742146647b17e0 https://doi.org/10.1016/j.morpho.2021.11.002 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....e6a7ddfab353d0ff28742146647b17e0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 12860115 |
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