Postoperative quality of life and therapy-related impairments of oral cancer in relation to time–distance since treatment
| العنوان: | Postoperative quality of life and therapy-related impairments of oral cancer in relation to time–distance since treatment |
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| المؤلفون: | Philipp Jehn, Philippe Korn, Gertrud Krüskemper, Nils-Claudius Gellrich, Fabian Matthias Eckstein, Frank Tavassol, Fritjof Lentge, Alexander-Nicolai Zeller, Simon Spalthoff, Michael-Tobias Neuhaus |
| المصدر: | Journal of Cancer Survivorship. 16:1366-1378 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, Oncology (nursing), business.industry, media_common.quotation_subject, Cancer therapy, Cancer, medicine.disease, Oncology, Quality of life, Surveys and Questionnaires, Quality of Life, Carcinoma, Squamous Cell, medicine, Breathing, Humans, Mouth Neoplasms, Neoplasm Recurrence, Local, Worry, Surgical treatment, business, Depression (differential diagnoses), Retrospective Studies, Rehabilitation Study, media_common |
| الوصف: | Oral cancer resection can cause physical and psychological impairments that influence the quality of life (QoL). Depending on the postoperative time–distance, the occurrence and intensity of these impairments may change. We evaluated the sequelae and changes in therapy-related impairments during the postoperative course to detect associations between the time since surgery and the presence of disorders. Data from a questionnaire completed by 1359 patients who underwent surgical treatment of oral squamous cell carcinoma and were involved in a multicenter rehabilitation study of the German–Austrian–Swiss Cooperative Group on Tumors of the Maxillofacial Region (DOSAK) that included 43 oral and maxillofacial clinics in Germany, Austria, and Switzerland were retrospectively analyzed. Physical impairments, including those in appearance, mouth opening ability, ability to smell, gastric disorders, mandible mobility, breathing, and shoulder/arm mobility, were significantly associated with and increased with time–distance since surgery. Esthetic appearance most strongly correlated with the highest perception of worsening. Regarding psychological disorders, worry about tumor recurrence, depression, and worse prospects were significantly associated. Among the postoperative sequelae, fear of tumor recurrence decreased continuously; however, depression and worse prospects increased. The general QoL did not significantly differ overall during the postoperative course. Therapy-related impairments change during the postoperative course based on the time–distance since surgery. The general QoL may not markedly vary; however, single impairments, to some extent, can increase or decrease. Continuous adaptation of supportive cancer therapy is required during follow-up to sufficiently address individual treatment needs. |
| تدمد: | 1932-2267 1932-2259 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f3e533cd81049535adc7432f764b00 https://doi.org/10.1007/s11764-021-01118-3 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....e6f3e533cd81049535adc7432f764b00 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 19322267 19322259 |
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