Combining Mean and Standard Deviation of Hounsfield Unit Measurements from Preoperative CT Allows More Accurate Prediction of Urinary Stone Composition Than Mean Hounsfield Units Alone
| العنوان: | Combining Mean and Standard Deviation of Hounsfield Unit Measurements from Preoperative CT Allows More Accurate Prediction of Urinary Stone Composition Than Mean Hounsfield Units Alone |
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| المؤلفون: | Yaniv Larish, John D. Denstedt, Hassan Razvi, Daniel Olvera-Posada, Leonard Glickman, Justin Amann, Brandon R Nadeau, Philippe D. Violette, Thomas Tailly, Husain Alenezi |
| المصدر: | Journal of Endourology. 30:453-459 |
| بيانات النشر: | Mary Ann Liebert Inc, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Urology, Urinary stone, Youden's J statistic, 030232 urology & nephrology, Standard deviation, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Hounsfield scale, medicine, Humans, Retrospective Studies, Calcium Oxalate, Medical treatment, business.industry, Area under the curve, Middle Aged, medicine.disease, Surgery, ROC Curve, Area Under Curve, 030220 oncology & carcinogenesis, Female, Urinary Calculi, Kidney stones, Tomography, X-Ray Computed, Nuclear medicine, business, CALCIUM OXALATE MONOHYDRATE |
| الوصف: | The mineral composition of a urinary stone may influence its surgical and medical treatment. Previous attempts at identifying stone composition based on mean Hounsfield Units (HUm) have had varied success. We aimed to evaluate the additional use of standard deviation of HU (HUsd) to more accurately predict stone composition.We identified patients from two centers who had undergone urinary stone treatment between 2006 and 2013 and had mineral stone analysis and a computed tomography (CT) available. HUm and HUsd of the stones were compared with ANOVA. Receiver operative characteristic analysis with area under the curve (AUC), Youden index, and likelihood ratio calculations were performed.Data were available for 466 patients. The major components were calcium oxalate monohydrate (COM), uric acid, hydroxyapatite, struvite, brushite, cystine, and CO dihydrate (COD) in 41.4%, 19.3%, 12.4%, 7.5%, 5.8%, 5.4%, and 4.7% of patients, respectively. The HUm of UA and Br was significantly lower and higher than the HUm of any other stone type, respectively. HUm and HUsd were most accurate in predicting uric acid with an AUC of 0.969 and 0.851, respectively. The combined use of HUm and HUsd resulted in increased positive predictive value and higher likelihood ratios for identifying a stone's mineral composition for all stone types but COM.To the best of our knowledge, this is the first report of CT data aiding in the prediction of brushite stone composition. Both HUm and HUsd can help predict stone composition and their combined use results in higher likelihood ratios influencing probability. |
| تدمد: | 1557-900X 0892-7790 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70a4fb7ce40e254571b0f37560f9ec1 https://doi.org/10.1089/end.2015.0209 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....e70a4fb7ce40e254571b0f37560f9ec1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1557900X 08927790 |
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