Mycobacterium hassiacum: a thermophilic Mycobacterium species to demonstrate thermal disinfection of medical devices
| العنوان: | Mycobacterium hassiacum: a thermophilic Mycobacterium species to demonstrate thermal disinfection of medical devices |
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| المؤلفون: | Marie-Claude Gagnon, Bruno Haas, Kelly J. Soto, Philippe Labrie, Jodi R. Alt, Dana S. Day, Alexander C. Roy |
| المصدر: | BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020) BMC Research Notes |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Thermal disinfection, Thermal resistance, 030106 microbiology, lcsh:Medicine, General Biochemistry, Genetics and Molecular Biology, Mycobacterium, Food and drug administration, 03 medical and health sciences, lcsh:Science (General), lcsh:QH301-705.5, Mycobacterium hassiacum, Microbial Viability, biology, Log reduction, Thermophile, lcsh:R, Temperature, Water, General Medicine, biology.organism_classification, Pulp and paper industry, Disinfection, Research Note, 030104 developmental biology, Equipment and Supplies, lcsh:Biology (General), Medical devices, Environmental science, Mycobacterium species, lcsh:Q1-390, Mycobacterium terrae |
| الوصف: | Objective Reprocessing reusable medical devices is crucial in the healthcare industry. To ensure patient safety, strict standards are dictated to validate thermal disinfection in automated washer-disinfectors. The United States Food and Drug Administration (FDA) has specific recommendations on the vegetative bacterial challenge but comparatively vague guidance on the use of a thermophilic Mycobacterium strain for thermal disinfection studies. This study aims to compare thermal resistance of Mycobacterium hassiacum and Mycobacterium terrae and determine which strain is suitable for medical device thermal disinfection validation testing in automated washer-disinfectors. Results Thermal resistance was demonstrated in vitro by calculating D-values for each strain at different exposure temperatures, and correlated with actual in situ processing conditions. M. terrae was completely killed (> 7 log reduction) at temperatures above 68 °C, with D-values between 46.6 and 27.8 s at temperatures between 59.5 and 67.2 °C. M. hassiacum was completely killed (> 8 log reduction) at temperatures above 75 °C, with D-values between 82.1 and 21.7 s at temperatures ranging between 69.2 and 73.6 °C. In vitro results were correlated in a washer-disinfector performance validation setup. |
| تدمد: | 1756-0500 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c3615a6339206642feb1123591f157 https://doi.org/10.1186/s13104-020-04978-7 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e7c3615a6339206642feb1123591f157 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 17560500 |
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