Prevalence of possible idiopathic normal pressure hydrocephalus in older inpatients with schizophrenia: a replication study
| العنوان: | Prevalence of possible idiopathic normal pressure hydrocephalus in older inpatients with schizophrenia: a replication study |
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| المؤلفون: | Hideo Morino, Yukiyo Miyoshi, Shu-ichi Ueno, Masayuki Nakamura, Shinichiro Ochi, Hokuto Omachi, Naoya Takeda, Yuta Yoshino, Yuki Ozaki, Taku Yoshida, Saori Inoue, Yumina Tachibana, Noriko Yamauchi, Mutsuhiko Mizobuchi, Jun-ichi Iga, Masao Abe |
| المصدر: | BMC Psychiatry, Vol 20, Iss 1, Pp 1-10 (2020) BMC Psychiatry |
| بيانات النشر: | BMC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, Pediatrics, medicine.medical_specialty, lcsh:RC435-571, Population, Disproportionately enlarged subarachnoid space, Urinary incontinence, 03 medical and health sciences, Cerebrospinal fluid tap test, 0302 clinical medicine, Neuroimaging, Japan, Normal pressure hydrocephalus, lcsh:Psychiatry, medicine, Prevalence, Dementia, Humans, education, Aged, education.field_of_study, Inpatients, business.industry, medicine.disease, Gait, Hydrocephalus, Normal Pressure, 030227 psychiatry, Hydrocephalus, Psychiatry and Mental health, Schizophrenia, Female, medicine.symptom, business, Drug-induced extra-pyramidal symptoms scale, 030217 neurology & neurosurgery, Research Article |
| الوصف: | Background We recently reported that older patients with schizophrenia (SZ) show possible idiopathic normal pressure hydrocephalus (iNPH) more frequently than the general population. In this study, we estimated the prevalence of iNPH in a larger number of older SZ patients and explored useful examination values for diagnosis in the SZ population. Methods We enrolled older inpatients with SZ (n = 39, mean age = 68.6 ± 7.7 years) from several psychiatric hospitals in Ehime, Japan and acquired brain imaging data using computed tomography. We evaluated three iNPH symptoms (dementia, gait disturbance, and urinary incontinence). In addition, we combined these data with our previous data to elucidate the relationship between iNPH and characteristics of SZ symptoms. Results In total, five (12.8%) patients were diagnosed with possible iNPH. Evans’ index for patients with iNPH was significantly higher than for those without iNPH (p = 0.002). The number of disproportionately enlarged subarachnoid space hydrocephalus (DESH) findings was significantly higher in patients with iNPH than in those without iNPH (p Conclusions We reconfirmed that older inpatients with SZ experienced possible iNPH more frequently than the general population. We should pay attention to the DIEPSS subscales of gait and bradykinesia and DESH findings in addition to the three main symptoms of iNPH and Evans’ index so as to not miss SZ patients with iNPH. |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d89489ca4084d4a1bed5f21bf03255 http://link.springer.com/article/10.1186/s12888-020-02690-1 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e7d89489ca4084d4a1bed5f21bf03255 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |