Hepatitis C Virus Transmission Clusters in Public Health and Correctional Settings, Wisconsin, USA, 2016–20171
| العنوان: | Hepatitis C Virus Transmission Clusters in Public Health and Correctional Settings, Wisconsin, USA, 2016–20171 |
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| المؤلفون: | Audrey F. Prieve, Ryan P. Westergaard, Ruth Koepke, Damien C. Tully, Karen A. Power, Karli R Hochstatter, Thomas Whyte, Todd M. Allen, David J. Bean, David W. Seal, Wajiha Z. Akhtar |
| المصدر: | Emerging Infectious Diseases |
| بيانات النشر: | Centers for Disease Control and Prevention (CDC), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Microbiology (medical), medicine.medical_specialty, Epidemiology, Hepatitis C virus, 030231 tropical medicine, Hepacivirus, medicine.disease_cause, molecular epidemiology, Drug Users, 03 medical and health sciences, Wisconsin, 0302 clinical medicine, injection drug use, Environmental health, medicine, Humans, viruses, hepatitis, 030212 general & internal medicine, Substance Abuse, Intravenous, Hepatitis C Virus Transmission Clusters in Public Health and Correctional Settings, Wisconsin, USA, 2016–2017, Phylogeny, Retrospective Studies, Hepatitis, Wisconsin usa, Molecular epidemiology, business.industry, Transmission (medicine), Research, Public health, global hepatitis outbreak surveillance technology, Outbreak, medicine.disease, Hepatitis C, United States, phylogenetics, Infectious Diseases, Prisons, transmission clusters, Female, Public Health, business |
| الوصف: | Ending the hepatitis C virus (HCV) epidemic requires stopping transmission among networks of persons who inject drugs. Identifying transmission networks by using genomic epidemiology may inform community responses that can quickly interrupt transmission. We retrospectively identified HCV RNA-positive specimens corresponding to 459 persons in settings that use the state laboratory, including correctional facilities and syringe services programs, in Wisconsin, USA, during 2016-2017. We conducted next-generation sequencing of HCV and analyzed it for phylogenetic linkage by using the Centers for Disease Control and Prevention Global Hepatitis Outbreak Surveillance Technology platform. Analysis showed that 126 persons were linked across 42 clusters. Phylogenetic clustering was higher in rural communities and associated with female sex and younger age among rural residents. These data highlight that HCV transmission could be reduced by expanding molecular-based surveillance strategies to rural communities affected by the opioid crisis. |
| وصف الملف: | application/pdf |
| تدمد: | 1080-6059 1080-6040 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e856bb87808cba0339510168fc9679a2 https://doi.org/10.3201/eid2702.202957 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e856bb87808cba0339510168fc9679a2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10806059 10806040 |
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